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Coma and confirmed epileptiform activity induced by Amanita pantherina poisoning.
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Bergamo Poison Center, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy.
Amanita pantherina poisoning is a rare event poorly described. The clinical picture is usually associated with the one of A. muscaria, but A.
View Article and Find Full Text PDFEnhancing Forensic Laboratories Through University Collaboration: Obtaining Conclusive Reports and Reference Materials via NMR.
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Pharmacy Department, Health Sciences School, University of Brasília, Brasília, Federal District, Brazil.
Forensic laboratories play a pivotal role in identifying and quantifying drugs in police seizures, often using spectroscopic techniques in combination with chromatographic methods that rely on chemical reference substances (CRS). The demand for a wide variety of CRS is critical, not only for common drugs like cocaine but also for the rapidly increasing number of new psychoactive substances (NPS), which emerge weekly. However, acquiring CRS is costly and bureaucratic because of the restricted circulation of these substances.
View Article and Find Full Text PDFAccidental Detection of Cocaine in Urine in Pediatric Patients: Case Series and Literature Review.
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October 2024
Responsible GAIA Service, Meyer Children's Hospital IRCCS, Viale Pieraccini 24, 50139 Florence, Italy.
Infantile occult exposure to cocaine in domestic environments represents a complex clinical and medico-legal problem, which can be associated with abuse and neglect and with potential short- and long-term health risks for children. The authors present a retrospective study on 764 children under 14 years old who accessed the Emergency Department of IRCCS Meyer from 2016 to 2023 and were included in the GAIA (Child and Adolescent Abuse Group) protocol for suspected maltreatment and abuse, and for which a urine toxicology analysis was performed. The aim is to discuss the medico-legal implications and highlight the need for a thorough evaluation and management of such situations.
View Article and Find Full Text PDFExtreme bradycardia in a case of benzodiazepine intoxication in a "body stuffer" (Bradicardia extrema en un caso de intoxicación por benzodiacepinas en un "body stuffer").
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Universidad del Rosario, Resident physician of the Pontificia Universidad Javeriana, Colombia.
Transport intoxication in the form of body stuffing, a dangerous practice involving the ingestion or insertion of psychoactive substances into the body to evade detection during drug trafficking, represents a major medical problem that requires immediate attention in the emergency department. Unlike body packing, where substances are encapsulated and swallowed for later extraction, body stuffing involves direct ingestion without wrapping, which greatly increases the risk of serious intoxication and even death. Benzodiazepines, due to their high demand on the black market, are among the most common drugs used in body stuffing.
View Article and Find Full Text PDF75 years of forensic profiling: A critical review.
Heliyon
October 2024
Department of Law, University of Bergamo, Via Moroni 255, 24127, Bergamo, Italy.
Article Synopsis
- The study of drug characterization began in 1948, mainly to trace the origins of opium, and has since evolved into various methods including geo-profiling and chemical attribution signatures (CAS) for substances like fentanyl.
- Forensic profiling has expanded to include different analytical techniques and products, focusing on the chemical properties and origins of both natural and synthetic drugs, which aids in tactical and strategic intelligence in law enforcement.
- The future of forensic profiling faces challenges due to organized crime, but advanced techniques like chemometrics and isotope ratio analysis provide critical support in combating illegal drug production and enhancing public health safety.
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