Ketamine is a versatile analgesic that has become an increasingly popular recreational drug. Chronic ketamine use has been found to cause biliary duct damage and bladder dysfunction. Ketamine-induced cholangiopathy and ulcerative cystitis are uncommon diagnoses presenting with nonspecific symptoms, creating diagnostic challenges for emergency physicians. We report a case of a teenage patient with the rare simultaneous presentation of ketamine-induced cholangiopathy and ulcerative cystitis. Due to increased recreational and chronic ketamine use, cases of ketamine-induced cholangiopathy and ulcerative cystitis are likely to rise with the increased knowledge, awareness, and reporting of these entities by radiologists and emergency physicians.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajem.2020.12.025 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Features of biliary tract diseases in ketamine abusers: a systematic review of case reports.
J Med Case Rep
March 2024
Department of Physical Medicine and Rehabilitation, School of Medicine, Shiraz University of Medical Sciences, Zand St., Shiraz, 71348-14336, Iran.
Background And Aims: Anesthesiologists prefer ketamine for certain surgeries due to its effectiveness as a non-competitive inhibitor of the N-methyl-D-aspartate receptor in the brain. Recently, this agent has also shown promise as an antidepressant. However, ketamine can cause hallucinogenic effects and is sometimes abused as an illicit drug.
View Article and Find Full Text PDFPatterns of ketamine use among people with substance use disorder in France: Multisource analysis of the data from the French Addictovigilance Network.
Fundam Clin Pharmacol
October 2024
U1106 Aix-Marseille Université, Inserm, Marseille, France.
Article Synopsis
- Ketamine is increasingly being used non-medically, especially among individuals with substance use disorders, with a notable rise in users from 2012 to 2021 according to data from the OPPIDUM program.
- Analysis of the French National Pharmacovigilance Database between 2020 and 2022 revealed that a significant proportion of ketamine cases involved complications like ketamine use disorder and symptoms related to urinary and liver issues.
- The findings highlight a concerning trend of growing ketamine use among substance users and associated health complications, although the overall non-medical use rates in the general population remain unclear.
Secondary Sclerosing Cholangitis After SARS-CoV2: ICU Ketamine Use or Virus-Specific Biliary Tropism and Injury in the Context of Biliary Ischemia in Critically Ill Patients?
Hepat Med
August 2023
Chief of Division of Internal Medicine and metabolism, Department of Internal Medicine, University Hospital of Modena, Modena, Italy.
Purpose: From the beginning of the Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV2) pandemic, different cases of a cholangiopathy with features of secondary sclerosing cholangitis in critically ill patients (SSC-CIP) have been reported. Patients developing it are generally recovering from severe Coronavirus disease 19 (COVID-19) and required intensive care unit (ICU) admission and mechanical ventilation. Many of them have been administered with ketamine during their ICU stay.
View Article and Find Full Text PDFSevere Ketamine-Induced Uropathy Associated With Cholangiopathy Requiring Percutaneous Nephrostomy.
Cureus
October 2022
Critical Care Medicine, New York Presbyterian Queens, Flushing, USA.
Ketamine-induced uropathy (KIU) is becoming more prevalent as ketamine abuse becomes widespread. Recently, a plethora of reports have highlighted the association between recreational ketamine abuse and its deleterious effects including uropathy and cholangiopathy. However, there are hardly any reports that demonstrate the management of severe KIU in young people.
View Article and Find Full Text PDFKetamine-induced cholangiopathy in ARDS patients.
Intensive Care Med
October 2021
Department of Anesthesiology and Critical Care and Burn Unit, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier St-Louis-Lariboisière, Paris, France.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!