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http://dx.doi.org/10.1016/j.eururo.2020.12.014DOI Listing

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Context: Lower Urinary Tract Symptoms (LUTS) are defined by their distressing effect on patients' day-to-day life. Given the pressures on secondary care resources, LUTS may be overlooked or inadequately assessed and therefore patients may be burdened for an extended period before treatment.

Methods: In a debate held at the International Consultation on Incontinence Research Society (ICI-RS) meeting in Bristol in June 2024, we considered how new technologies might contribute to an expedited, dignified and effective investigation of LUTS.

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Aims: Urinary tract infections are one of the most common reasons for antibiotic prescription. The widespread use of antibiotic treatments contributes to the global health problem of antimicrobial resistance development. To slow down the progression of antimicrobial resistance, it is essential that we explore nonantibiotic preventive treatments for this common condition.

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Bidirectional relationships between depression, anxiety and urinary symptoms in women: A prospective cohort study.

J Affect Disord

January 2025

Bristol Medical School, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, United Kingdom of Great Britain and Northern Ireland.

Article Synopsis
  • - The study explores whether depression and anxiety lead to lower urinary tract symptoms (LUTS) in middle-aged women, and whether these symptoms later contribute to depression.
  • - Based on data from the Avon Longitudinal Study, findings show that depression is linked to various types of urinary incontinence and urgency, while anxiety is only associated with nightly urination (nocturia).
  • - The results indicate a complex relationship where mental health issues could influence LUTS, and vice versa, suggesting a need for further research to understand these connections better.
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Interleukins are a diverse group of cytokines that play a crucial role in controlling immune responses and have potential as biomarkers. This mini review evaluates 12 recent papers linking urinary interleukins to both urinary infection and systemic diseases. While measurement of serum interleukins can indicate systemic inflammation, urinary interleukins provide more specific insights into renal or urinary tract inflammation.

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