Dispersion of cellulose nanocrystals (CNCs) is of utmost importance to guarantee their reliable application. Nevertheless, there is still no consensual method to characterize CNC aggregation. The hypothesis of this paper is that dispersion could be quantified through the classification of aggregates detected in transmission electron microscopy images. k-Means was used to classify image particulate elements of five CNC samples into groups according to their geometric features. Particles were classified into five groups according to their maximum Feret diameter, elongation, circularity and area. Two groups encompassed the most application-critical aggregates: one integrated aggregates of high complexity and low compactness while the other included elongated aggregates. In addition, the characterization of CNC dispersion after different levels of sonication was achieved by assessing the change in the number of elements belonging to each cluster after sonication. This approach could be used as a standard for the characterization of the aggregation state of CNCs.
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http://dx.doi.org/10.1016/j.carbpol.2020.117271 | DOI Listing |
Sleep Adv
December 2024
Department of Allergy, Division of Pediatric Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital, Chicago, IL, USA.
Study Objectives: The complete blood count (CBC) is one of the most commonly ordered blood tests with a large range of reference values that does not consider time of day for interpretation. Our objective was to systematically review this topic to report on peak and trough timing of CBC values.
Methods: A systematic search was performed for studies evaluating any component of the CBC with at least three collections over 24 hours.
Front Cell Infect Microbiol
December 2024
Postdoctoral Research Workstation, Heilongjiang Academy of Agricultural Sciences, Harbin, China.
Lactic acid bacteria are widely regarded as safe alternatives to antibiotics in livestock and poultry farming and have probiotic potential. () is a prominent component of pigeon crop microbiota; however, its function is unknown. In this study, a strain of 1003 from pigeon cecum was identified by combining whole genome sequencing and phenotypic analysis, and its safety and probiotic properties were studied.
View Article and Find Full Text PDFCureus
November 2024
Pulmonary Medicine, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, ITA.
Pulmonary alveolar microlithiasis (PAM) is a rare lung disorder characterized by calcium phosphate microliths in the alveolar spaces. Autosomal recessive mutations on the SLC34A2 gene lead to altered type IIb sodium phosphate cotransporter in alveolar type-II cells of the lung, thus resulting in aggregations of microliths in the alveoli. To date, more than 1000 cases have been reviewed by expert pulmonary clinicians.
View Article and Find Full Text PDFAtherosclerosis is a chronic inflammatory disease affecting the vascular system, characterised by the accumulation of modified lipoproteins, immune cell aggregation and the development of fibrous tissue within blood vessel walls. As atherosclerosis impacts blood vessels, its adverse effects may manifest across various tissues and organs. In this review, we examine the association of atherosclerosis with Alzheimer's disease, stroke, pancreatic and thyroid dysfunction, kidney stones and chronic kidney diseases.
View Article and Find Full Text PDFToxicol Appl Pharmacol
December 2024
Yu-Yue Pathology Scientific Research Center, Chongqing 400039, PR China; Jinfeng Laboratory, Chongqing 400039, PR China. Electronic address:
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Due to the poor therapeutic efficacy of CRC treatments and poor prognosis of the disease, effective treatment strategies are urgently needed. As long-term proteotoxic stress is a major cause of cell death, agents that induce proteotoxic stress offer a promising strategy for cancer intervention.
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