AI Article Synopsis
- Hexavalent chromium (Cr(VI)) is known to have harmful effects including cancer and toxicity to organs such as the kidneys, liver, and nervous system.
- The study focused on the impact of Cr(VI) on developing chicken embryos, finding that higher doses significantly reduced the hatchability of chicks, while lower doses did not show major changes.
- Even at potentially harmful levels, lower doses of Cr(VI) did not appear to cause notable hematological or liver changes in newly hatched chicks.
Article Abstract
Hexavalent chromium (Cr(VI)) has carcinogenic, nephrotoxic, hepatotoxic, and neurotoxic effects. Exposure to Cr(VI) can also lead to hematological alterations and blood biochemical changes. The literature on Cr(VI) toxicity concerns mostly adult forms of vertebrates. In this study, an attempt was made to determine the effect on the developing chicken embryo of Cr(VI) in ovo administration. It was observed that chromium affected the hatchability of chicks in a dose-dependent manner. At a dose from 25 to 250 μg per egg, Cr(VI) resulted in a statistically significant reduction of hatchability. Chromium administrated at lower doses (1.56 and 2.5 μg per egg) caused a statistically insignificant increase of hatchability. However, chromium at a level of LD (15.6 μg per egg) or 1/10 LD (1.56 per egg) did not cause major changes in hematological parameters or plasma biochemical indices in newly hatched chicks. The same doses did not lead to any histopathological changes in the liver.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772708 | PMC |
| http://dx.doi.org/10.1016/j.psj.2020.10.016 | DOI Listing |
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