Necrotizing Bacterial Rhinitis in an Immunocompromised Patient.

Ear Nose Throat J

Department of Otorhinolaryngology-Head and Neck Surgery, 37798"G. Papanikolaou" General Hospital, Thessaloniki, Greece.

Published: December 2022

AI Article Synopsis

  • Specific bacterial infections can quickly damage the nasal mucosa in immunocompromised patients, resembling fungal infections.
  • Prompt exclusion of fungal infection is critical, as rapid deterioration can lead to death within a short time frame.
  • To ensure accurate treatment, doctors rely on histopathology and tissue cultures, as empirically prescribing Amphotericin B can cause harmful side effects.

Article Abstract

Specific bacterial infections can cause rapid necrosis of the nasal mucosa in immunocompromised patients, mimicking an invasive fungal infection. The exclusion of the latter is a priority because rapid deterioration and death may ensue within hours to days. The time lag between investigations and final diagnosis warrants empiric administration of Amphotericin B but patients are exposed to significant side effects. Histopathology and culture of the nasal tissues provide the necessary diagnostic clues to avoid inappropriate treatment.

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Source
http://dx.doi.org/10.1177/0145561320984994DOI Listing

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