AI Article Synopsis
- Adrenal cortical carcinoma (ACC) is a rare and aggressive tumor that often comes with a poor prognosis, and around 60% of cases are functional tumors.
- Bilateral ACC, occurring in only 2%-10% of cases, is particularly uncommon; the detection of this using F-FDG PET/CT imaging has not previously been reported.
- In this case study, a male patient with Cushing's syndrome was diagnosed with left ACC, and F-FDG PET/CT helped confirm bilateral ACC as well as staging metastasis to lymph nodes and lungs.
Article Abstract
Adrenal cortical carcinoma (ACC) is a rare aggressive endocrine tumor with poor prognosis. About 60% of ACC are functional tumors. Bilateral ACC is extremely rare, roughly 2%-10% of cases. Diagnosis and staging of ACC by imaging modalities are crucial for preoperative planning and prognostication. Detection of hyperfunctional bilateral adrenocortical carcinoma by 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F- FDG PET/CT) has never been reported. Herein, we report a male patient who presented with Cushing's syndrome, type II diabetes mellitus due to Cushing's syndrome, and hypogonadism with biopsy confirmed left ACC. He underwent F-FDG PET/CT to evaluate the contralateral adrenal mass and to plan for laparoscopic adrenalectomy, which subsequently confirmed bilateral ACC. Furthermore, F-FDG PET/CT was useful in staging, which revealed paraaortic lymph node and lung metastasis.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745877 | PMC |
| http://dx.doi.org/10.4103/wjnm.WJNM_86_19 | DOI Listing |
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