On 21 February 2020, a violent COVID-19 outbreak, which was initially concentrated in Lombardy before infecting some surrounding regions exploded in Italy. Shortly after, on 9 March, the Italian Government imposed severe restrictions on its citizens, including a ban on traveling to other parts of the country. No travel, no virus spread. Many regions, such as those in southern Italy, were spared. Then, in June 2020, under pressure for the economy to reopen, many lockdown measures were relaxed, including the ban on interregional travel. As a result, the virus traveled for hundreds of kilometers, from north to south, with the effect that areas without infections, receiving visitors from infected areas, became infected. This resulted in a sharp increase in the number of infected people; i.e., the daily count of new positive cases, when comparing measurements from the beginning of July to those from at the middle of September, rose significantly in almost all the Italian regions. Upon confirmation of the effect of Italian domestic tourism on the virus spread, three computational models of increasing complexity (linear, negative binomial regression, and cognitive) have been compared in this study, with the aim of identifying the one that better correlates the relationship between Italian tourist flows during the summer of 2020 and the resurgence of COVID-19 cases across the country. Results show that the cognitive model has more potential than the others, yet has relevant limitations. The models should be considered as a relevant starting point for the study of this phenomenon, even if there is still room to further develop them up to a point where they become able to capture all the various and complex spread patterns of this disease.
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http://dx.doi.org/10.3390/s20247319 | DOI Listing |
Knee
January 2025
Department of Radiology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
Background: Long-leg alignment and joint line obliquity have traditionally been assessed using two-dimensional (2D) radiography, but the accuracy of this measurement has remained unclear. This study aimed to evaluate the accuracy of 2D measurements of lateral distal femoral angle (LDFA) and medial proximal tibial angle (MPTA) using upright three-dimensional (3D) computed tomography (CT).
Methods: This study involved 66 knees from 38 patients (34 women, four men) with knee osteoarthritis (OA), categorized by Kellgren-Lawrence (KL) grade.
J Perianesth Nurs
January 2025
Medical Faculty, Department of Anesthesia and Reanimation, Giresun Üniversitesi, Giresun, Türkiye. Electronic address:
Purpose: The aim in the present study was to evaluate the effects of chewing postoperative xylitol gum on gastrointestinal functional recovery after laparoscopic cholecystectomy.
Design: A three-arm randomized controlled trial.
Methods: After a baseline assessment, participants were randomly assigned in three groups.
BMC Pulm Med
January 2025
Department of Key Laboratory of Ningxia Stem Cell and Regenerative Medicine, Institute of Medical Sciences, Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Background: In this study, we aimed to explore the association between baseline and early changes in the neutrophil-to-lymphocyte ratio (NLR) and the 30-day mortality rate in patients having anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis with interstitial lung disease (DM-ILD).
Methods: Overall, 263 patients with anti-MDA5 DM-ILD from four centers in China were analyzed. Multivariate logistic regression analysis was used to evaluate the impact of baseline NLR on the 30-day mortality rate in patients with anti-MDA5-positive DM-ILD.
BMC Med Genomics
January 2025
Department of Surgery, Faculty of General of Medicine, Koya University, Koya, Kurdistan Region - F.R., KOY45, Iraq.
Background: During mammalian spermatogenesis, the cytoskeleton system plays a significant role in morphological changes. Male infertility such as non-obstructive azoospermia (NOA) might be explained by studies of the cytoskeletal system during spermatogenesis.
Methods: The cytoskeleton, scaffold, and actin-binding genes were analyzed by microarray and bioinformatics (771 spermatogenic cellsgenes and 774 Sertoli cell genes).
BMC Infect Dis
January 2025
Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15 West 7, Kita-ku, Sapporo, 060-8638, Japan.
Background: Mycobacterium avium complex (MAC) is a common pathogen causing non-tuberculous mycobacterial infections, primarily affecting the lungs. Disseminated MAC disease occurs mainly in immunocompromised individuals, such as those with acquired immunodeficiency syndrome, hematological malignancies, or those positive for anti-interferon-γ antibodies. However, its occurrence in solid organ transplant recipients is uncommon.
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