Sputum interleukin-6 (IL-6) level is high during acute chest syndrome (ACS) in pediatric sickle cell disease, supporting anti–IL-6 trials. Sputum IL-8, CCL2, and CCL3 levels are also high during ACS, possibly contributing to recruitment of inflammatory cells in the lungs.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756999 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2020003519 | DOI Listing |
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