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The Effect of Metabolic Bariatric Surgery on Cardiovascular Risks: A Prospective Study Measuring Antibodies to Apolipoprotein A-1.
Obes Surg
January 2025
Cairo University Hospitals, Cairo, Egypt.
Background: Obesity is a chronic disease associated with other associated medical problems, including atherogenic dyslipidemia. Metabolic bariatric surgery (MBS) has been shown to reduce long-term cardiovascular risk (CVR). Anti-ApoA-1 antibodies (AAA1) are independently associated with cardiovascular disease, which remains a major cause of death in individuals with obesity.
View Article and Find Full Text PDFCoagulation in familial hypercholesterolemic patients: effect of current hypolipidemic treatment and anticoagulants.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Familial hypercholesterolemia (FH) is a relatively rare genetic disease associated with high serum cholesterol levels but also with abnormalities in blood coagulation. Novel pharmacotherapeutic approaches in FH including proprotein convertase subtilisin/kexin type 9 antibodies (PCSK9Ab) are very efficient in decreasing cholesterol levels but their impact on coagulation in FH is not yet established. Therefore, we hypothesized that these novel antidyslipidemic drugs can positively impact blood coagulation due to their more potent effect on cholesterol.
View Article and Find Full Text PDFCardiovascular risk profile with SCORE2 and SCORE2-OP: comparing Portugal, Spain, Italy, and France using the new European predictive models.
Front Cardiovasc Med
December 2024
Departamento Medicina Interna, Hospital Lusíadas Lisboa, Lisboa, Portugal.
Introduction: This study aims to characterize the cardiovascular risk profile in countries with low-to-moderate cardiovascular mortality risk (Italy, Portugal, France, and Spain) using the SCORE2 and SCORE2-OP models. It also examines regional variations and the involvement of healthcare professionals in performing risk assessments.
Methods: A retrospective observational study was conducted using data from 24,434 cardiovascular risk assessments performed between December 2022 and July 2023 through a digital application used by physicians.
Impact of ultra-processed foods on excess weight and dyslipidemia in schoolchildren.
Nutrition
November 2024
Graduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Research and Innovation Laboratory in Sports and Nutrition Sciences, Institute of Food and Nutrition, Multidisciplinary Center - Federal University of Rio de Janeiro, Macaé, Brazil.
Objective: To analyze the impact of the association between the consumption of ultra-processed foods (UPF), excess weight, and dyslipidemia in schoolchildren.
Methods: This is a cross-sectional study in which 420 schoolchildren aged 6 to 10 years from public schools in the municipality of Rio das Ostras, Brazil, were evaluated. Food consumption was assessed using the Previous Day Food Questionnaire (PDFQ-3), and physical activity (PA) was assessed using the Previous Day Physical Activity and Food Questionnaire (PDPAFQ).
The relevance of remnant cholesterol as a guide for lipid management in Indian subjects undergoing coronary revascularization.
Diabetes Metab Syndr
December 2024
Division of Cardiothoracic Surgery, Medanta- The Medicity, Gurgaon, India.
Background: The atherogenic potential of remnant cholesterol, which refers to the cholesterol content of triglyceride-rich, non-low-density lipoprotein (LDL) particles in circulation, has gained increasing attention recently. Unfortunately, very limited information is available regarding remnant cholesterol levels in Indian subjects.
Methods: This was a retrospective study conducted at a premier, tertiary care center in North India.
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