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[Advances in studies on steroidal alkaloids and their pharmacological activities in genus Veratrum]. | LitMetric

[Advances in studies on steroidal alkaloids and their pharmacological activities in genus Veratrum].

Zhongguo Zhong Yao Za Zhi

Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College Hangzhou 310013, China.

Published: November 2020

AI Article Synopsis

  • * These alkaloids have various pharmacological effects, primarily known for lowering blood pressure, preventing blood clots, reducing inflammation, providing pain relief, and having anti-cancer properties.
  • * The paper aims to classify and summarize these steroidal alkaloids and their health benefits to support future research and application of these compounds.

Article Abstract

Genus Veratrum plants contain a diversity of steroidal alkaloids, so far at least 184 steroidal alkaloids attributed to cevanine type(A-1~A-69), veratramine type(B-1~B-21), jervanine type(C-1~C-31), solanidine type(D-1~D-10) and verazine type(E-1~E-53), respectively, have been isolated and identified in the genus Veratrum. Their pharmacological activities mainly focused on decreasing blood pressure, anti-platelet aggregation and anti-thrombosis, anti-inflammatory and analgesic, and antitumor effect. This paper classified and summarized the 184 kind of steroidal alkaloids from the Veratrum plants and their major pharmalogical activities in order to provide the scientific basis for the further development and utilization of active alkaloids.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20200612.201DOI Listing

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