Rare facial clefts are characterized by facial involvement that is not restricted to the lip, palate, and alveolus as in traditional cleft lip and palate. The craniofacial skeleton and the orbital structures are frequently affected in these conditions. Exposure of the eyeball, when not early treated, puts the function and the preservation of the eye at risk. We report the case of a 2-month-old boy admitted to our service with an extensive oral-ocular cleft and exposure of the eyeball with melting corneal ulcer treated with a conjunctival closure with a purse-string suture.
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http://dx.doi.org/10.1177/1055665620980632 | DOI Listing |
Ophthalmic Plast Reconstr Surg
October 2024
Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, U.S.A.
Purpose: To evaluate the long-term outcomes of enucleation without conjunctival closure in a large patient cohort.
Methods: A retrospective chart review was conducted from January 2011 to January 2024, examining 144 eyes of 143 patients who underwent enucleation without conjunctival closure by a single oculoplastic surgeon. Data collected included patient demographics, indications for surgery, implant types, and complications.
Eur J Ophthalmol
December 2024
Ophthalmology Glaucoma Department, Fundación Oftalmológica Médica de la Comunidad Valenciana (FOM), Valencia, Spain.
Introduction: To present a novel surgical technique for the treatment of a steep-walled filtering bleb following an Ahmed glaucoma valve implant. The primary aim was to alleviate the patient's discomfort and address associated corneal thinning, complications that can arise from this condition.
Methods: Case report and surgical technique.
Ocul Surf
October 2024
Department of Clinical Regenerative Medicine, Fujita Health University, Japan. Electronic address:
Purpose: This study explores the application of adipose-derived mesenchymal stromal cells (adMSCs) as a therapy for ocular inflammatory diseases utilizing a chronic GVHD model.
Methods: Human adMSCs were administered via subconjunctival injection into mice with chronic ocular GVHD. Clinical scores and changes in T cell populations were analyzed.
Bilateral limbal stem cell deficiency (LSCD) is a significant cause of corneal blindness and is more difficult to treat, as compared with unilateral LSCD because no source of autologous limbal stem cells (LSCs) remains in these patients. Thus, bilateral patients could be candidates for treatment with allogeneic LSC transplants that require long-term systemic immunosuppression therapy. Thus, if possible, for the correct candidates, using autologous LSCs could be a preferred treatment.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
July 2024
Department of Ophthalmology, College of Medicine, Qassim University, Saudi Arabia.
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