Contamination with the fungus Alternaria spp. is often considered to have originated from laboratory sources, which occasionally causes infection in immunocompromised patients, termed as phaeohyphomycosis. Here, we have reported a case of cutaneous alternariosis caused by Alternaria alternata. This diagnosis was based on microscopic examination and mycological culturing of patient's vesicular lesions, with the use of 5 molecular markers (namely, ITS, ATPase, Actin, rpb2, and tef1) for strain identification. We noted that Alternaria infection caused an increase in the serum level of (1-3)-β-D-glucan (BG) in the patients. To the best of our knowledge, no such finding has been reported in previously in the literature.
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http://dx.doi.org/10.1016/j.micpath.2020.104703 | DOI Listing |
Indian J Dermatol Venereol Leprol
October 2024
Department of Dermatology, Shandong Provincial Institute of Dermatology and Venereology, Shandong Province, Jinan, Shandong, China.
Mycopathologia
September 2024
Department of Dermatology, CHU Rouen, 1 Rue Germont, 76000, Rouen, France.
Turk Patoloji Derg
September 2024
Department of Pathology, Karnataka Institute of Medical Sciences, KARNATAKA, INDIA.
To document a case of `preliminary` identification of Alternaria sp (a phaeohyphomycotic agent) based on morphology in tissue section in a patient with allergic fungal rhinosinusitis. A 25-year-old male, a known asthmatic in a post Covid -19 state, presented with headache, facial swelling and nasal block with discharge of brownish mucoid material. Debrided material from the right maxillary antrum and middle turbinate showed brownish mucoid material admixed with firm to hard degenerated bony spicules sent in formalin and subjected for histopathological examination.
View Article and Find Full Text PDFJ Mycol Med
September 2024
Division of Infectious Diseases and Tropical Medicine, Moffitt Cancer Center, Tampa, FL, USA.
Phaeohyphomycoses are infections caused by dark-walled dematiaceous fungi. Alternaria and Curvularia are two genera of dematiaceous molds known to cause invasive fungal rhinosinusitis, particularly in immunocompromised patients. Co-infection with two dematiaceous fungi is rarely reported in the literature.
View Article and Find Full Text PDFVopr Pitan
April 2024
Federal Research Centre for Nutrition, Biotechnology and Food Safety, 109240, Moscow, Russian Federation.
Tomatoes and tomato products are widely produced and consumed throughout the world. Alternaria spp. are the main cause of alternariosis (black mold disease) on fresh tomatoes, both in the field and after harvesting.
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