A chemoselective as well as enantioselective fluorescent probe has been developed to determine both the concentration and enantiomeric composition of the biologically important amino acid histidine by measuring the fluorescence responses when excited at two different wavelengths.
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http://dx.doi.org/10.1039/d0cc07498e | DOI Listing |
Pest Manag Sci
January 2025
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, China.
Background: Indoxacarb, a type of chiral pesticide, is used to control Lepidoptera insects. Most studies had focused on the environmental behavior and selective toxicity of indoxacarb enantiomers, and the mechanism behind its selective biological activity against target organisms is not well understood.
Results: Spodoptera frugiperda was selected as the target insect.
J Org Chem
January 2025
Chemistry Department, Georgetown University, Washington, D.C. 20057, United States.
The reaction between a chiral carboxylic acid molecule and 1,1'-bis(diphenylphosphino)ferrocenepalladium dichloride in the presence of a mild base generates a chiroptically active metal complex displaying strong circular dichroism (CD) signals in the visible light region, a highly sought-after goal in the optical sensing realm. The molecular recognition process is complete within a few minutes and can be used for fast chiroptical determination of the enantiomeric composition and concentration of carboxylic acid samples. This method is operationally simple and broadly applicable to a large variety of structures including important drugs, natural products, amino acids, and hydroxy acids.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Chemistry, University of Virginia, Charlottesville, VA 22904, United States. Electronic address:
Amino acids play important roles in human pathology and physiology and the qualitative and quantitative determination of chiral amino acids in humans and mammals also has important impacts on the life sciences. Therefore, the introduction of artificial probes to assess the concentrations and enantiomeric compositions [ee = ([D] - [L])/([D] + [L])] of amino acids in aqueous solution is necessary in understanding certain biological processes and diagnosing and treating diseases. Herein, a bifunctional achiral coumarin probe (Br-Coumarin) is reported to determine the absolute configuration, ee value, and concentration of 16 amino acids in THF/HO = 1/4 solution at micromolar concentrations.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Department of Chemistry, Soongsil University, Seoul, 06978, South Korea. Electronic address:
Chiral Au@Pt nanoparticles (NPs) with optically plasmonic and catalytic active surfaces were sustainably prepared to serve as label-free surface enhanced Raman scattering (SERS) platform to distinguish D- and L-enantiomers of alanine and tartaric acid. Surface morphologies were characterized by high-angle annular dark-field imaging-scanning transmission electron microscopy (HADDF-STEM) and selected area energy diffraction (SAED) patterns. The amounts of Pt on chiral Au NPs were estimated by the inductively coupled plasma-optical emission spectrometer (ICP-OES) and X-ray diffraction (XRD).
View Article and Find Full Text PDFAnal Chim Acta
January 2025
National Engineering Laboratory/Key Laboratory of Henan Province, Henan University of Technology, Zhengzhou, 450001, China. Electronic address:
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