AI Article Synopsis
- Pleomorphic adenoma (PA) is the most common benign salivary gland tumor, but tracheobronchial PA is rare, with fewer than 50 documented cases, including a recently reported case of a 49-year-old woman treated for asthma.
- The patient experienced significant breathing difficulties and diagnostic imaging revealed a 2.4 cm obstruction in the lower trachea, leading to a diagnosis of tracheal PA based on histopathological findings.
- Tracheobronchial PA is typically diagnosed around age 48, affects both genders equally, commonly presents with cough and other respiratory symptoms, and generally has a low chance of recurrence.
Article Abstract
Background: Pleomorphic adenoma (PA) is the most common benign tumor that occurs in the salivary glands; however, tracheobronchial PA is rarely observed. To the best of our knowledge, fewer than 50 cases have been reported in the literature. We report a 49-year-old woman who had been treated for asthma for 2 years before being diagnosed with PA of the trachea.
Case Summary: A 49-year-old woman was referred to our hospital due to dyspnea upon exertion and chronic cough with wheezing for 2 years. Laboratory tests showed an elevated white blood cell count, absolute neutrophil count, and percentage of neutrophils. A chest computerized tomography scan showed a well-defined, soft-tissue density lesion measuring 2.4 cm × 2.1 cm in the lower trachea. Flexible bronchoscopy revealed that nearly 90% of the tracheal lumen was obstructed. The histopathological and immunohistochemistry features suggested PA of the trachea. Furthermore, we review the characteristics of 29 patients with tracheobronchial PA over the last 30 years.
Conclusion: Tracheobronchial PA occurs without gender predominance, mostly in the lower or upper trachea, and has a low recurrence rate. The median age at diagnosis is 48 years. The most common symptoms are cough, stridor, dyspnea, and wheezing.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723722 | PMC |
| http://dx.doi.org/10.12998/wjcc.v8.i23.6026 | DOI Listing |
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