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Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology
January 2025
Department of Digestion, Metabolism and Reproduction, Institute of Reproductive and Developmental Biology, Hammersmith Campus, Imperial College London, London, UK.
Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis in Leydig cells and in the ovary in theca, luteal, and luteinizing granulosa cells. Low levels in LHCGR are also expressed in numerous extragonadal sites.
View Article and Find Full Text PDFNeuropathology in 1984: a deadly shot into the heart of Europe.
Free Neuropathol
January 2024
Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University Vienna, Vienna, Austria.
Just 40 years ago, Europe was divided into the Eastern communist bloc, which included the Czechoslovak Socialist Republic (ČSSR) and was dominated by the now historical Soviet Union, and the Western bloc comprising democracies such as Austria. The Iron Curtain, a heavily guarded and deadly border zone, separated the two blocs and constrained, in prison style, the populations of the Eastern bloc. The present neuropathological article relates the sad fate of František Faktor, a 33 years-old Czech who was shot by ČSSR border guards when attempting to flee to Austria at the border between and .
View Article and Find Full Text PDFMusical neglect training for chronic persistent left hemispatial neglect with right hemiplegia post-stroke: a case report.
Front Rehabil Sci
January 2025
Department of Rehabilitation, Shiragikuen Hospital, Kochi, Japan.
A 69-year-old right-handed man, who initially suffered a stroke 8 years ago and experienced two recurrences since then, presented with right hemiplegia and left hemispatial neglect as a post-stroke syndrome in the chronic phase. This report demonstrates the use of active musical instrument playing with Musical Neglect Training (MNT®) to improve severe left-side neglect and activities of daily living (ADLs). In addition to physical and occupational therapy, individual MNT® was incorporated into the patient's rehabilitation plan to improve his hemispatial neglect.
View Article and Find Full Text PDFRemoval of an incarcerated intrauterine device reaching the serosal surface of the uterus by hysteroscopy alone: a case report.
Front Med (Lausanne)
January 2025
Department of Gynecology and Obstetrics, International Peace Maternity and Child Health Hospital Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Embryo Original Diseases, Shanghai Municipal Key Clinical Specialty, Shanghai, China.
Background: An intrauterine device (IUD) is a widely used long-term contraceptive device for family planning. However, the IUD can lead to various complications. Severe complications and remedial measures caused by IUDs have been reported in the literature; however, detailed surgical approaches for safely removing the IUD within the minimum surgical range have rarely been described especially in postmenopausal women.
View Article and Find Full Text PDFTowards a sustainable set of European Core Health Indicators (ECHI).
J Health Monit
December 2024
National Institute for Public Health and the Environment (RIVM), Centre for Public Health, Healthcare and Society, Bilthoven, The Netherlands.
Background: The European Core Health Indicators (ECHI) are a set of 88 indicators that provide a compact overview of the extensive field of European public health and healthcare. The ECHI set adds value to European Union health information systems (HIS) for both Member States and EU-associated countries and the European Commission by providing a solid, comparable information base on national public health and healthcare trends and developments. The indicators allow for learning by comparison and the list supports the organisation of national health information systems.
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