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Quantitative susceptibility mapping reveals brain iron accumulation in minimal hepatic encephalopathy: associations with neurocognitive changes.
Metab Brain Dis
November 2024
Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Brain iron deposition is correlated with minimal hepatic encephalopathy (MHE). This study aimed to investigate the pattern of altered iron distribution, using quantitative susceptibility mapping (QSM), and to clarify the relationship between iron deposition and neurocognitive changes in MHE. We enrolled 32 cirrhotic patients without MHE (NHE), 21 cirrhotic patients with MHE, and 24 healthy controls, and used the Psychometric Hepatic Encephalopathy Score (PHES) to assess neurocognitive function.
View Article and Find Full Text PDFMyocardial fibrosis is associated with brain microstructural alterations in patients with heart failure: A diffusion MRI study.
Eur J Radiol
January 2025
Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China. Electronic address:
Purpose: This study aimed to examine the changes in brain diffusion in patients with heart failure (HF) by measuring the apparent diffusion coefficient (ADC) and to investigate the relationship between these changes and cardiac injury features.
Methods: The study included 49 patients with HF and 39 healthy controls. Cognitive performance was assessed using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA).
Pediatric Neural Changes to Physical and Emotional Pain After Intensive Interdisciplinary Pain Treatment: A Pilot Study.
Clin J Pain
November 2024
Pain Management, Department of Pediatrics, Children's Mercy Hospital.
Objective: Brain areas activated during pain can contribute to enhancing or reducing the pain experience, showing a potential connection between chronic pain and the neural response to pain in adolescents and youth.
Methods: This study examined changes in brain activation associated with experiencing physical pain and observing physical and emotional pain in others by using functional magnetic resonance imaging (fMRI) before and after intensive interdisciplinary pain treatment (IIPT). Eighteen youths (age 14 to 18) with widespread chronic pain completed fMRI testing before and after IIPT to assess changes in brain activation in response to physical and emotional pain.
Differential diagnosis of posterior scalp hair loss.
Arch Dermatol Res
November 2024
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
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