Background: In total hip arthroplasty the surgeon aims to restore the biomechanics of the joint. Femoral height has the greatest influence on restoring limb length and contributes equally to the restoration of femoral head centre. On X-ray, the level of femoral neck resection is most often referenced off the upper border of lesser trochanter. Less frequently, femoral head centre is referenced from the tip of the greater trochanter. The error in measurement of femoral height resulting from unknown femoral rotation is crucially important and can result in inappropriate surgical planning for implant selection and placement. It is unknown which reference produces lower error.
Methods: A sample of femoral shapes was generated using a femoral statistical shape model. These were placed in a range of orientations in terms of external rotation and flexion, at intervals of 10°. Simulated X-rays were then produced and the distances from the tip of either greater or lesser trochanter to femoral head centre were measured.
Findings: Although using greater trochanter as a reference demonstrated greater errors at the extremes, both techniques resulted in errors of 7-8 mm with 20° of both femoral external rotation and flexion.
Interpretation: Moderate degrees of femoral external rotation combined with flexion can result in unsatisfactory errors when templating limb length. There should be greater focus and an agreed definition for femoral height. There is a clinical need for a method with a lower error in determining true femoral height and the level of neck resection.
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http://dx.doi.org/10.1016/j.clinbiomech.2020.105247 | DOI Listing |
J Cell Biochem
January 2025
Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China.
tRNA-derived fragments (tRFs) are a newly recognized class of small noncoding RNAs (sncRNAs) that play significant roles in various diseases. The Wnt pathway plays a key role in various physiological processes such as embryonic development, tissue renewal and regeneration. In the regulation of Wnt/β-catenin, Forkhead box k1(FOXK1), Frizzled class receptor 3 (FZD3), and Wnt5b can be targeted and inhibited by three tRFs: tRF3008A targets FOXK1 to inhibit colorectal cancer (CRC), 5'-tiRNAVal targets FZD3 to inhibit breast cancer (BrC), and tRF-22-8BWS7K092 targets Wnt5b to induce ferroptosis in lung cells.
View Article and Find Full Text PDFCureus
December 2024
Orthopaedic Surgery, Showa University School of Medicine, Tokyo, JPN.
Introduction This study evaluated hip joint dynamic instability in patients with non-traumatic osteonecrosis of the femoral head (ONFH) with extensive lesions, who had undergone anterior rotational osteotomy (ARO) and high-degree posterior rotational osteotomy (HDPRO), based on the femoral head translation observed by computed tomography (CT) at 0° and 45° hip flexion. Materials and methods Medical records of patients who had undergone transtrochanteric rotational osteotomy for non-traumatic ONFH were retrospectively reviewed to identify patients who had undergone CT examinations six weeks post-operatively. In all, 64 hips (60 patients; 19 men and 41 women), comprising 36 hips treated with HDPRO and 28 hips treated with ARO, respectively, were included.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopaedics, Liaocheng People's Hospital, Liaocheng, Shandong, P.R. China.
Background: Vitamin E-diffused highly cross-linked polyethylene (HXLPE/Vit E) is a relatively advanced material used in total hip arthroplasty (THA) but whether it shows superiority is unclear.
Objective: This meta-analysis was performed to investigate the effect of HXLPE/Vit E liners in THA.
Methods: Medline/PubMed, Embase and Cochrane Library databases were searched to retrieve studies assessing the efficacy of HXLPE/Vit E liners in THA with the design of a randomized, controlled trial.
Eur J Trauma Emerg Surg
January 2025
Orthopedic Clinic Olgahospital, Klinikum Stuttgart, Kriegsbergstraße 62, 70173, Stuttgart, Germany.
Background: Pediatric femoral neck fractures (PFNF) are rare but associated with a high rate of serious complications such as avascular femoral head necrosis (AVN). Major risk factors and prognostic tools for an AVN are still unclear. As AVN is a devastating complication, this study aims to evaluate the predictors for AVN following a PFNF.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Spine and Spinal Cord Surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Jinshui District, Zhengzhou, 450003, Henan, China.
The use of pulsed electromagnetic field (PEMF) has demonstrated effectiveness in the management of femoral head osteonecrosis as well as nonunion fractures; however, the effects of PEMF on preventing glucocorticoid-induced osteoporosis (GIOP) have not been extensively studied. The aim of this investigation was to explore the effectiveness of PEMF stimulation in averting GIOP in rats and uncover the potential fundamental mechanisms involved. A total of seventy-two adult male Wistar rats composed the experimental group and were subsequently assigned to three groups for treatment.
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