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http://dx.doi.org/10.1016/S0140-6736(20)32706-9 | DOI Listing |
Sci Rep
October 2020
Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, Hertfordshire, UK.
Idiopathic epilepsy (IE) is the most common chronic neurological condition in dogs, characterised by recurrent seizure activity and associated with negative behavioural and cognitive changes. We hypothesised that IE would negatively impact putative affective state, with dogs with IE exhibiting a more pessimistic judgement bias and more negative attention bias than controls. Dogs were tested in a previously-validated spatial judgement bias task, and a novel auditory attention bias task testing attention to sounds with different valence or salience (neutral, novel pre-habituated, threatening).
View Article and Find Full Text PDFVet Rec
September 2020
Dogs Trust, 17 Wakley Street, London EC1V 7RQ.
J Neuroimmune Pharmacol
June 2021
Department of Biomedical Sciences, University of New England College of Osteopathic Medicine, 11 Hills Beach Road, Biddeford, ME, 04005, USA.
HIV affects 37 million people worldwide, 25-69% of which develop HIV-associated neurocognitive disorders (HAND) regardless of antiviral treatment. HIV infection of the brain decreases cognitive function, disrupts/impairs learning and memory, and reduces quality of life for those affected. HIV-induced neuroinflammation has been associated with viral proteins such as gp120 and Tat, which remain elevated in the CNS even in patients with low peripheral viremia counts.
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