AI Article Synopsis
- The study aimed to assess the risk of choroidal neovascularization (CNV) in eyes with angioid streaks (AS) and irregular vascular networks (IVN).
- Patients with AS and IVN were monitored over 18 months using advanced imaging techniques to detect any development of CNV.
- Findings suggested that IVN can predict the emergence of CNV, indicating the need for regular monitoring and timely treatment to manage potential complications.
Article Abstract
Purpose: To evaluate the risk of active choroidal neovascularization (CNV) in presence of deep irregular vascular network (IVN) in eyes with angioid streaks (AS).
Methods: Observational case series including three treatment-naive eyes with angioid streaks and IVN, without CNV. Patients were followed-up during 18 months with multimodal imaging including structural optical coherence tomography (OCT) and OCT Angiography (OCT-A) to detect possible neovascular complication.
Results: On OCT-A, IVN was detected as a peripapillary and/or macular high-flow lesion, filling the spaces between the angioid streaks in the outer retina slab. Repeated OCT-A could detect an active CNV emerging from the IVN, as a high-flow rich anastomotic vascular network with a perilesional dark halo. Patient was treated with intravitreal injections of Bevacizumab on a Pro Re Nata regimen, with a decreased CNV area and lower vascular density on control OCT-A.
Conclusion: OCT-A shown to be helpful in detecting the presence of IVN in asymptomatic eyes with AS during a routine examination. In our series, the IVN seems to be predictor of active CNV, needing a close surveillance and frequent follow-up to allow early treatment upon CNV activation.
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| http://dx.doi.org/10.1177/1120672120974292 | DOI Listing |
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