Purpose: This case report highlights the functional and quality-of-life outcomes of an 8-week treadmill training program for an 18-month old child with Williams syndrome who is not walking.
Summary Of Key Points: The child had clinical improvements in gross motor function and quality of life as determined by the Gross Motor Function Measure and Pediatric Quality of Life Inventory after 8 weeks of treadmill training as an outpatient.
Statement Of Conclusion And Recommendations For Clinical Practice: Treadmill training is clinically feasible and effective for this child with Williams syndrome. Further research is necessary for generalizability. Treadmill training should be considered when developing a plan of care for children with Williams syndrome who are not walking or children with similar deficits.
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http://dx.doi.org/10.1097/PEP.0000000000000770 | DOI Listing |
Life Sci Space Res (Amst)
February 2025
Department of Biomedical Engineering, Center for Injury Biomechanics, Wake Forest University School of Medicine. 575 N. Patterson Avenue, Suite 530. Winston-Salem, NC 27101, USA. Electronic address:
Muscle atrophy occurs with extended exposure to microgravity. This study quantified the overall muscle size, lean muscle area and fat infiltration changes pre- to post-flight that occur in the thoracic and lumbar spine with long-duration spaceflight. Pre- and post-flight magnetic resonance imaging (MRI) scans were obtained from 9 crewmembers on long-duration (≥6 months) International Space Station (ISS) missions.
View Article and Find Full Text PDFNutrients
January 2025
BiOSSE, Biology of Organisms, Stress, Health, Environment, Institut Universitaire de Technologie, Département Génie Biologique, Le Mans Université, 53020 Laval, France.
Background: Physical activity, such as running, protects against cardiovascular disease and obesity but can induce oxidative stress. Athletes often consume antioxidants to counteract the overproduction of reactive oxygen and nitrogen species during exercise. , particularly its phycocyanin content, activates the Nrf2 pathway, stimulating antioxidant responses.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Department of Physical Therapy, Daejeon Health University, Daejeon 30711, Republic of Korea.
Background: Virtual reality-based training has been widely used for post-stroke patients due to its positive effects on functional aspects by promoting brain plasticity.
Objective: This study aimed to investigate the effectiveness of gait training with virtual reality-based real-time feedback on motor function, balance, and spatiotemporal gait parameters in post-stroke patients.
Methods: Fifteen patients ( = 15) with chronic stroke were randomly assigned to either the virtual reality-based real-time feedback with treadmill gait training (experimental group = 8) or the treadmill gait training (control group = 7).
J Appl Physiol (1985)
January 2025
School of Sport, Exercise, and Health Science; Loughborough University (UK).
This study assessed the cardiorespiratory fitness, running biomechanics, muscle architecture and training characteristics of a 76-year-old female runner who currently holds the world record 1500m to marathon in the women's 75-79 age category. maximal oxygen uptake (V̇O), running economy (RE), lactate threshold (LT) and lactate turnpoint (LTP), maximal heart rate (HR), and running biomechanics were measured during a discontinuous treadmill protocol followed by a maximal incremental test. Muscle architecture was assessed using ultrasound.
View Article and Find Full Text PDFAm J Hum Biol
January 2025
Department of Physical Education and Sport, University of Granada, Granada, Spain.
Introduction: The maximal fat oxidation (MFO) and the exercise intensity that provokes MFO (FATMAX) are inversely associated with cardiometabolic risk factors in healthy young sedentary adults. However, how both cardiorespiratory fitness (CRF) level and sex influence MFO during exercise and the FATMAX is seldom analyzed.
Objectives: This study is aimed at determining the influence of CRF and sex on MFO.
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