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Color Tuning of Fluorogens for FAST Fluorogen-Activating Protein. | LitMetric
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Color Tuning of Fluorogens for FAST Fluorogen-Activating Protein.

Ivan N Myasnyanko Alexey S Gavrikov Snizhana O Zaitseva Alexander Yu Smirnov Elvira R Zaitseva Anatolii I Sokolov Kseniya K Malyshevskaya Nadezhda S Baleeva Alexander S Mishin Mikhail S Baranov

Chemistry

Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997, Moscow, Russia.

Published: February 2021

Using benzylidene imidazolone core, we created a panel of color-shifted fluorogenic ligands for FAST protein without compromise to the binding efficiency and the utility for live-cell protein labeling. This study highlights the potential of benzylidene imidazolones derivatives for rapid expansion of a pallet of live-cell fluorogenic labeling tools.

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 Source
http://dx.doi.org/10.1002/chem.202004760DOI Listing

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