Multiscale Validation of Multiple Human Body Model Functional Spinal Units.

J Biomech Eng

Biomechanics + Accident Analysis Institute of Legal Medicine, University of Munich, Munich 80336, Germany.

Published: April 2021

A validation comparing five human body model (HBM) lumbar spines is carried out across two load cases, with the objective to use and apply HBMs in high strain rate applications such as car occupant simulation. The first load case consists of an individual intervertebral disc (IVD) loaded in compression at a strain rate of 1/s by a material testing machine. The second load case is a lumbar functional spine unit (FSU) loaded in compression using a drop tower setup, producing strain rates of up to 48/s. The IVD simulations were found to have a better agreement with the experiments than the FSU simulations, and the ranking of which HBMs matched best to the experiment differed by load case. These observations suggest the need for more hierarchical validations of the lumbar spine for increasing the utility of HBMs in high strain rate loading scenarios.

Download full-text PDF

Source
http://dx.doi.org/10.1115/1.4049332DOI Listing

Publication Analysis

Top Keywords

strain rate
12
load case
12
human body
8
body model
8
hbms high
8
high strain
8
loaded compression
8
multiscale validation
4
validation multiple
4
multiple human
4

Similar Publications

Immobilization of Peniophora incarnata F1 in PVA-SA-biochar matrix and its degradation performance and mechanism for erythromycin degradation.

J Environ Manage

January 2025

Changzhou Key Laboratory of Biomass Green, Safe and High Value Utilization Technology, Institute of Urban and Rural Mining, Changzhou University, No.21 Gehu Road, Wujin District, Changzhou, 213164, China; National-Local Joint Engineering Research Center for Biomass Refining and High-Quality Utilization, Changzhou University, No.21 Gehu Road, Wujin District, Changzhou, 213164, China. Electronic address:

Erythromycin is becoming one of the most common contaminants detected in surface water and wastewater, which poses a potential risk to ecological systems and human health. Until now, there is still no effective way to eliminate it. Herein, a novel and efficient erythromycin-degrading fungus Peniophora incarnata F1, capable of utilizing erythromycin as its sole source of carbon and energy, was isolated from contaminated sludge.

View Article and Find Full Text PDF

Background: Neonatal sepsis (NNS) is a known cause of morbidity and mortality especially in developing countries. The global resistance scourge may worsen the management outcomes of NNS. This study aims to determine the current profile of bacteriological agents of NNS, their resistance status and associated mortality in our setting.

View Article and Find Full Text PDF

Despite extensive experience with influenza surveillance in humans in Senegal, there is limited knowledge about the actual situation and genetic diversity of avian influenza viruses (AIVs) circulating in the country, hindering control measures and pandemic risk assessment. Therefore, as part of the "One Health" approach to influenza surveillance, we conducted active AIV surveillance in two live bird markets (LBMs) in Dakar to better understand the dynamics and diversity of influenza viruses in Senegal, obtain genetic profiles of circulating AIVs, and assess the risk of emergence of novel strains and their transmission to humans. Cloacal swabs from poultry and environmental samples collected weekly from the two LBMs were screened by RT-qPCR for H5, H7, and H9 AIVs.

View Article and Find Full Text PDF

Coronavirus disease 2019 (COVID-19) has been associated with a significant fatality rate and persistent evolution in immunocompromised patients. In this prospective study, we aimed to determine the duration of excretion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 37 Tunisian patients with hematological malignancies (40.5% with lymphoma and 37.

View Article and Find Full Text PDF

Atypical porcine pestivirus (APPV) was first identified in 2015 in North America by high-throughput sequencing. APPV is associated with congenital tremor A-II and is widely distributed worldwide. In this study, a total of 2630 samples of domestic pigs obtained from 14 regions of Russia from 2020 to 2024 were screened for APPV presence by qRT-PCR.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!