AI Article Synopsis

  • The text discusses the medicinal fungus, highlighting its historical use in folk medicine and extensive research on its biological functions, particularly focusing on its immunomodulatory effects.
  • Different extracts of the fungus, including total extracts and polysaccharides, have varying influences on immune responses: some encourage type 1 immunity while others favor type 2 immunity.
  • The article is pioneering in categorizing these immunomodulatory effects and aims to offer insights for both healthy individuals and those with weakened immune systems regarding the fungus's use.

Article Abstract

() is a fungus with a long history of widespread use in folk medicine, and its biological and medicinal functions are well studied. A crucial pharmacological effect of is immunomodulation. In this review, we catalog the immunomodulatory effects of different extracts of , namely total extracts, polysaccharides and cordycepin Total extracts obtained using water or 50% ethyl alcohol and polysaccharides from were discovered to tend to promote type 1 immunity, whereas total extracts obtained using 70-80% ethyl alcohol and cordycepin from were more likely to promote type 2 immunity. This article is the first to classify the immunomodulatory effects of different extracts of . In addition, we discovered a relationship between different segments or extracts and differing types of immunity. This review can provide the readers a comprehensive understanding on the immunomodulatory effects of the precious folk medicine and guidance on its use for both health people and those with an immunodeficiency.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735063PMC
http://dx.doi.org/10.3389/fphar.2020.575704DOI Listing

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