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Polynomial-Time Statistical Estimation of Species Trees Under Gene Duplication and Loss. | LitMetric

AI Article Synopsis

Article Abstract

Phylogenomics-the estimation of species trees from multilocus data sets-is a common step in many biological studies. However, this estimation is challenged by the fact that genes can evolve under processes, including incomplete lineage sorting (ILS) and gene duplication and loss (GDL), that make their trees different from the species tree. In this article, we address the challenge of estimating the species tree under GDL. We show that species trees are under a standard stochastic model for GDL, and that the polynomial-time algorithm ASTRAL-multi, a recent development in the ASTRAL suite of methods, is under this GDL model. We also provide a simulation study evaluating ASTRAL-multi for species tree estimation under GDL.

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http://dx.doi.org/10.1089/cmb.2020.0424DOI Listing

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