Aim: To identify the effect of enhanced recovery after surgery (ERAS) and rapid rehabilitation concepts on the outcomes of patients with haemophilia A undergoing total knee arthroplasty.

Design: Randomized controlled trial.

Methods: The primary endpoint was postoperative hospital stay. The secondary endpoints were pain scores, joint function scores, haemoglobin levels at 3 and 7 days after surgery and satisfaction with hospitalization.

Results: Thirty-two patients were enrolled. Compared with the routine nursing group, the ERAS group showed shorter postoperative hospital stay (14.2 0.8 vs. 16.6 ± 1.3 days,  < .001), smaller amounts of blood transfusion (924 317 vs. 1,263 449 ml,  = .020) and coagulation factors (37,325 5,996 vs. 48,475 8,019 U,  < .001), lower pain scores at 3 (3.3 0.7 vs. 4.3 0.7,  = .002) and 7 (2.3 SD 0.7 vs. 2.8 ± 0.5,  = .015) days, lower hospital for special surgery knee scores at 3 (59.9 7.8 vs. 53.6 SD 5.9,  = .016) and 7 (77.9 6.9 vs. 71.1 ± 7.1,  = .009) days and higher satisfaction with hospitalization (94.3 1.4 vs. 92.7 1.6,  = .004).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729805PMC
http://dx.doi.org/10.1002/nop2.605DOI Listing

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