Deep brain stimulation (DBS) has been used in the treatment of motor diseases with remarkable safety and efficacy, which abet the interest of its application in the management of other neurologic and psychiatric disorders such as epilepsy. Experimental data demonstrated that electric current could modulate distinct brain circuits and decrease the neuronal hypersynchronization seen in epileptic activity. The ability to carefully choose the most suitable anatomical target as well as to define the most reasonable stimulation parameters is highly dependable on the comprehension of the underlying mechanisms of action, which remain unclear. This review aimed to explore the relevant clinical data regarding the use of DBS in the treatment of refractory epilepsy.
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http://dx.doi.org/10.4103/0028-3886.302454 | DOI Listing |
Neurosurg Rev
January 2025
School of Medicine, The University of Jordan, Amman, 11942, Jordan.
Deep brain stimulation (DBS) effectively treats Parkinson's disease (PD) motor symptoms, highlighting a gap in understanding current research trends and future directions. This study aims to analyze DBS literature systematically using bibliometric methods to map trends and identify opportunities. A total of 6,041 publications on DBS for PD from 1993 to 2023 were retrieved from the Web of Science Core Collection (WoSCC) on July 24, 2023.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Center for Functional Neurosurgery, Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Background: Parkinson's disease (PD) is primarily characterized by motor symptoms, but patients also experience a relatively high prevalence of non-motor symptoms, including emotional and cognitive impairments. While the subthalamic nucleus (STN) is a common target for deep brain stimulation to treat motor symptoms in PD, its role in emotion processing is still under investigation. This study examines the subthalamic neural oscillatory activities during facial emotion processing and its association with affective characteristics.
View Article and Find Full Text PDFComput Methods Programs Biomed
January 2025
Medical AI Lab, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518060, China. Electronic address:
Background And Objective: Neurosurgical navigation is a critical element of brain surgery, and accurate segmentation of brain and scalp blood vessels is crucial for surgical planning and treatment. However, conventional methods for segmenting blood vessels based on statistical or thresholding techniques have limitations. In recent years, deep learning-based methods have emerged as a promising solution for blood vessel segmentation, but the segmentation of small blood vessels and scalp blood vessels remains challenging.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Objective: This study aimed to assess the feasibility of the deep learning in generating T2 weighted (T2W) images from diffusion-weighted imaging b0 images.
Materials And Methods: This retrospective study included 53 patients who underwent head magnetic resonance imaging between September 1 and September 4, 2023. Each b0 image was matched with a corresponding T2-weighted image.
Phys Eng Sci Med
January 2025
Department of Electronics and Communication Engineering, Vishnu Institute of Technology, Bhimavaram, Andhra Pradesh, 534202, India.
Schizophrenia (SZ) is a chronic neuropsychiatric disorder characterized by disturbances in cognitive, perceptual, social, emotional, and behavioral functions. The conventional SZ diagnosis relies on subjective assessments of individuals by psychiatrists, which can result in bias, prolonged procedures, and potentially false diagnoses. This emphasizes the crucial need for early detection and treatment of SZ to provide timely support and minimize long-term impacts.
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