Deep neural networks achieve remarkable performance in many computer vision tasks. Most state-of-the-art (SOTA) semantic segmentation and object detection approaches reuse neural network architectures designed for image classification as the backbone, commonly pre-trained on ImageNet. However, performance gains can be achieved by designing network architectures specifically for detection and segmentation, as shown by recent neural architecture search (NAS) research for detection and segmentation. One major challenge though is that ImageNet pre-training of the search space representation (a.k.a. super network) or the searched networks incurs huge computational cost. In this paper, we propose a Fast Network Adaptation (FNA++) method, which can adapt both the architecture and parameters of a seed network (e.g., an ImageNet pre-trained network) to become a network with different depths, widths, or kernel sizes via a parameter remapping technique, making it possible to use NAS for segmentation and detection tasks a lot more efficiently. In our experiments, we apply FNA++ on MobileNetV2 to obtain new networks for semantic segmentation, object detection, and human pose estimation that clearly outperform existing networks designed both manually and by NAS. We also implement FNA++ on ResNets and NAS networks, which demonstrates a great generalization ability. The total computation cost of FNA++ is significantly less than SOTA segmentation and detection NAS approaches: 1737× less than DPC, 6.8× less than Auto-DeepLab, and 8.0× less than DetNAS. A series of ablation studies are performed to demonstrate the effectiveness, and detailed analysis is provided for more insights into the working mechanism. Codes are available at https://github.com/JaminFong/FNA.
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http://dx.doi.org/10.1109/TPAMI.2020.3044416 | DOI Listing |
JAMA
January 2025
Assistant Secretary for Technology Policy/Office of the National Coordinator for Health IT, Washington, DC.
Importance: Health information technology, such as electronic health records (EHRs), has been widely adopted, yet accessing and exchanging data in the fragmented US health care system remains challenging. To unlock the potential of EHR data to improve patient health, public health, and health care, it is essential to streamline the exchange of health data. As leaders across the US Department of Health and Human Services (DHHS), we describe how DHHS has implemented fundamental building blocks to achieve this vision.
View Article and Find Full Text PDFDig Dis Sci
January 2025
Ningxia Medical University, Xing Qing Block, Shengli Street No.1160, Yin Chuan City, 750004, Ningxia Province, People's Republic of China.
Background: Colon adenocarcinoma (COAD) is a leading cause of cancer-related mortality worldwide. Transient receptor potential vanilloid 4 (TRPV4), a calcium-permeable non-selective cation channel, has been implicated in various cancers, including COAD. This study investigates the role of TRPV4 in colon adenocarcinoma and elucidates its potential mechanism via the ferroptosis pathway.
View Article and Find Full Text PDFDiscov Oncol
January 2025
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Introduction: Colorectal cancer (CRC) is the second most common cause of cancer-related deaths globally. The gut microbiota, along with adenomatous polyps (AP), has emerged as a plausible contributor to CRC progression. This study aimed to scrutinize the impact of the FadA antigen derived from Fusobacterium nucleatum on the expression levels of the ANXA2 ceRNA network and assess its relevance to CRC advancement.
View Article and Find Full Text PDFDrugs Aging
January 2025
Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, 420 East 70th St, New York, NY, LH-36510063, USA.
There are several pharmacologic agents that have been touted as guideline-directed medical therapy for heart failure with preserved ejection fraction (HFpEF). However, it is important to recognize that older adults with HFpEF also contend with an increased risk for adverse effects from medications due to age-related changes in pharmacokinetics and pharmacodynamics of medications, as well as the concurrence of geriatric conditions such as polypharmacy and frailty. With this review, we discuss the underlying evidence for the benefits of various treatments in HFpEF and incorporate key considerations for older adults, a subpopulation that may be at higher risk for adverse drug events.
View Article and Find Full Text PDFBiochem Genet
January 2025
Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
This study aimed to identify shared gene expression related to circadian rhythm disruption in polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD) to discover common diagnostic biomarkers. Visceral fat RNA samples were collected from 12 PCOS and 14 non-PCOS patients, a sample size representing the clinical situation and sufficient to capture PCOS gene expression profiles. Along with liver transcriptome profiles from NAFLD patients, these data were analyzed to identify crosstalk circadian rhythm-related genes (CRRGs) between the diseases.
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