Background: The COVID-19 pandemic is challenging the public health response system worldwide, especially in poverty-stricken, war-torn, and least developed countries (LDCs).
Methods: We characterized the epidemiological features and spread dynamics of COVID-19 in Niger, quantified the effective reproduction number ( ), evaluated the impact of public health control measures, and estimated the disease burden.
Results: As of 4 July 2020, COVID-19 has affected 29 communes of Niger with 1093 confirmed cases, among whom 741 (67.8%) were males. Of them 89 cases died, resulting in a case fatality rate (CFR) of 8.1%. Both attack rates and CFRs were increased with age ( < 0.0001). Health care workers accounted for 12.8% cases. Among the reported cases, 39.3% were isolated and treated at home, and 42.3% were asymptomatic. 74.6% cases were clustered in Niamey, the capital of Niger. The fluctuated in correlation to control measures at different outbreak stages. After the authorities initiated the national response and implemented the strictest control measures, quickly dropped to below the epidemic threshold (<1), and maintained low level afterward. The national disability-adjusted life years attributable to COVID-19 was 1267.38 years in total, of which years of life lost accounted for over 99.1%.
Conclusions: Classic public health control measures such as prohibition of public gatherings, travelling ban, contact tracing, and isolation and quarantine at home, are proved to be effective to contain the outbreak in Niger, and provide guidance for controlling the ongoing COVID-19 pandemic in LDCs.
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http://dx.doi.org/10.7189/jogh.10.020513 | DOI Listing |
Diagn Progn Res
December 2024
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, 3508 GA, the Netherlands.
Background: We evaluated the performance of prognostic models for predicting mortality or ICU admission in hospitalized patients with COVID-19 in the World Health Organization (WHO) Global Clinical Platform, a repository of individual-level clinical data of patients hospitalized with COVID-19, including in low- and middle-income countries (LMICs).
Methods: We identified eligible multivariable prognostic models for predicting overall mortality and ICU admission during hospital stay in patients with confirmed or suspected COVID-19 from a living review of COVID-19 prediction models. These models were evaluated using data contributed to the WHO Global Clinical Platform for COVID-19 from nine LMICs (Burkina Faso, Cameroon, Democratic Republic of Congo, Guinea, India, Niger, Nigeria, Zambia, and Zimbabwe).
Infect Drug Resist
December 2024
Dunarea de Jos" University of Galati, Faculty of Medicine and Pharmacy, Galati, Romania.
Streptococcus pneumoniae is the main pathogen that plays a dual role, on the one hand as an asymptomatic carrier in the nasopharyngeal mucosa and on the other hand directly responsible for triggering invasive pneumococcal infections with various important localizations, especially in the pediatric population. Thus, invasive pneumococcal infections represent one of the main causes of mortality and morbidity in children under 5 years of age. Immunization is a key preventive measure against these infections.
View Article and Find Full Text PDFFront Public Health
December 2024
Sydani Group, Abuja, Nigeria.
Background: Developing countries have partnered with non-governmental and development organizations to ensure universal health coverage and promote equity in accessing health services. This study was motivated by the timely and relevant collaborative partnership among the National Primary Health Care Development Agency (NPHCDA), Sydani Consulting, and other implementing partners at the sub-national level. There is also no evidence of a study on partnership coordination vis-à-vis COVID-19 vaccine optimization.
View Article and Find Full Text PDFAntibiotics (Basel)
October 2024
Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Pulmonary aspergillosis is a severe respiratory infection caused by spp., whose resistance profiles and invasive attitude complicate therapeutical strategies. Several aspergillosis cases emerged as superinfections during the SARS-CoV-2 pandemic when isavuconazole and amphotericin B became essential antifungal alternatives.
View Article and Find Full Text PDFAnn Med Surg (Lond)
November 2024
Department of Neurosurgery, UHC Habib Bourguiba, Sfax, Tunisia.
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