The diagnosis of varicocele is clinical, carried out in supine and standing position and in Valsalva maneuver. Only clinical varicoceles have to be treated. A scrotal ultrasound with Doppler is generally performed as part of the infertile man's evaluation or in case of examination difficulties. The main indication for varicocele treatment is the adult man with clinical varicocele and abnormalities of sperm parameters, in a context of infertility of couple, with a partner having a satisfactory ovarian reserve and no cause of female infertility or a curable infertility cause. The decision to treat varicocele must therefore be taken after evaluation of the two partners of the couple. Adults with symptomatic varicocele and those with spermogram abnormalities may also be offered a cure for their varicocele even in the absence of a paternity plan, as well as adolescents with reduced testicular growth, an ipsilateral decrease testicular volume, or a size gradient between the 2 testes. The cure of varicocele can be carried out by surgery or by percutaneous embolization. Microsurgery (inguinal or subinguinal) offers lower rates of recurrence and complications than high surgical approaches (laparoscopic or not) and surgeries without magnification. It is therefore the reference surgical technique. Percutaneous retrograde embolization is a minimally invasive alternative to microsurgery offering satisfactory outcomes with rare and often benign complications. The cure for varicocele results in an improvement in sperm parameters and recent data seem to confirm that it increases the natural pregnancy rate. These results appear after a delay of 3 to 9 months (at least 1 to 2 cycles of spermatogenesis). When the sperm involvement was severe (azoospermia, severe oligospermia), the improvement of the spermogram allow (1) to avoid surgery testicular sperm extraction or (2) perform intrauterine insemination rather than ICSI.
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http://dx.doi.org/10.1016/j.purol.2020.11.006 | DOI Listing |
World J Mens Health
January 2025
Cleveland Clinic Foundation, Cleveland, OH, USA.
Prog Urol
November 2023
Service de médecine de la reproduction, hôpital des 4-Villes, Saint-Cloud, France.
Background: At a time when increasing attention is being paid to the limitations and risks of in vitro fertilisation techniques, surgeries to improve male fertility are attracting growing interest.
Methods: Systematic review based on a Pubmed search of surgeries to improve male fertility.
Results: Vasovasostomy (VV) gives patency rates of 70-97% and pregnancy rates of 30-76%.
Pan Afr Med J
November 2023
Département de Gynécologie Obstétrique, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Introduction: in Lubumbashi, as in upscale areas where explorations of fertility are very clever, the spermogram remains the essential analysis in the diagnosis of male infertility. This is the cause of 40% of couple infertility. The spermogram is the first step in identifying seminal abnormalities.
View Article and Find Full Text PDFWorld J Mens Health
January 2024
Department of Urology, School of Medicine and Health Sciences, University of Lusaka, Lusaka, Zambia.
Int J Mol Sci
December 2022
Department of Human Pathology of Adult and Childhood, University of Messina, 98125 Messina, Italy.
Varicocele is one of the main causes of infertility in men, thus representing an important clinical problem worldwide. Inflammation contributes mainly to its pathogenesis, even if the exact pathophysiological mechanisms that correlate varicocele and infertility are still unknown. In addition, oxidative stress, apoptosis, hypoxia, and scrotal hyperthermia seem to play important roles.
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