Introduction: We sought to (i) adapt a Spanish-language vaccine hesitancy (VH) tool to rural Guatemala, (ii) pilot the tool with 150 parents of children ≤ 5 years, and (iii) measure if parent scores associated with child under-vaccination.
Methods: We used implementation science to develop the adapted Guatemalan Vaccine Attitudes (GuaVA) tool, piloting it with 150 parents of children ≤ 5 years, and performing descriptive and adjusted regression analyses.
Results: Of 150 parents (response rate 99%), 55% (n = 83) of parents expressed a degree of VH. Children of parents with highly hesitant scores (n = 22) had 2.5 times the odds (OR 2.5; 95% CI: 1.2, 5.4) of being undervaccinated at 19 months, referent children of non-hesitant parents (n = 67).
Conclusions: Vaccine hesitancy may be more prevalent in rural Guatemala than suspected. Implementation science facilitated the adaptation of a VH tool to rural Guatemala and may assist investigators in other settings.
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http://dx.doi.org/10.1016/j.vaccine.2020.11.069 | DOI Listing |
PLoS One
January 2025
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
Background: Randomized controlled trials (RCTs) that evaluate the efficacy of an intervention remain underutilized in community-based environmental health research. RCTs that use a pragmatic design emphasize the effectiveness of interventions in complex, real world settings. Pragmatic trials may be especially relevant when community-based interventions address social and environmental determinants that threaten health equity.
View Article and Find Full Text PDFGlob Chang Biol
January 2025
School of Biological Sciences, The University of Hong Kong, Hong Kong, China.
Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e.
View Article and Find Full Text PDFKidney Int
December 2024
Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK.
The disadvantaged populations eGFR (estimated glomerular filtration rate) epidemiology (DEGREE) study was designed to gain insight into the burden of chronic kidney disease (CKD) of undetermined cause (CKDu) using standard protocols to estimate the general-population prevalence of low eGFR internationally. Therefore, we estimated the age-standardized prevalence of eGFR under 60 ml/min per 1.73m in adults aged 18-60, excluding participants with commonly known causes of CKD; an ACR (albumin/creatinine ratio) over 300 mg/g or equivalent, or self-reported or measured (HT) hypertension or (DM) diabetes mellitus, stratified by sex and location.
View Article and Find Full Text PDFPublic Health Chall
June 2024
Center for Global Health, Colorado School of Public Health, Aurora, Colorado, USA.
Background: Malnutrition is prevalent throughout southwest Guatemala, where >40% of children suffer from chronic undernutrition. Evidence supports that assessing a community's awareness and readiness to address malnutrition is a critical first step in improving the success of a nutrition intervention program. The objective of this study was to apply the community readiness model (CRM) to assess community readiness to address childhood malnutrition in a rural southwest region of Guatemala.
View Article and Find Full Text PDFAm J Disaster Med
December 2024
Department of Surgery, Hartford Hospital, Hartford, Connecticut.
Objective: This project aimed to successfully implement the Stop the Bleed (STB) program in Guatemala by targeting key providers in various communities across the country.
Setting: The course was conducted in rural community centers, fire stations, tertiary care centers, and medical school facilities.
Participants: We included agricultural occupational health workers, firefighters, medical providers, and medical students throughout the course.
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