Study Design: Retrospective case series.
Objective: Patient with metastatic cancer frequently require spinal operations for neural decompression and stabilization, most commonly thoracic vertebrectomy with reconstruction. Objective of the study was to assess economic aspects associated with use of cement versus expandable cage in patients with single level thoracic metastatic disease. We also looked at the differences in the clinical, radiological, complications and survival differences to assess non-inferiority of PMMA over cages.
Methods: The electronic medical records of patients undergoing single level thoracic vertebrectomy and reconstruction were reviewed. Two groups were made: PMMA and EC. Totals surgical cost, implant costs was analyzed. We also looked at the clinical/ radiological outcome, complication and survival analysis.
Results: 96 patients were identified including 70 one-level resections. For 1-level surgeries, Implant costs for use of cement-$75 compared to $9000 for cages. Overall surgical cost was significantly less for PMMA compared to use of EC. No difference was seen in clinical outcome or complication was seen. We noticed significantly better kyphosis correction in the PMMA group.
Conclusions: Polymethylmethacrylate cement offers significant cost advantage for reconstruction after thoracic vertebrectomy. It also allows for better kyphosis correction and comparable clinical outcomes and non-inferior to cages.
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http://dx.doi.org/10.1177/2192568220975375 | DOI Listing |
J Orthop Case Rep
November 2024
Department of Spine Surgery, Zydus Hospitals and Healthcare Research Private Limited, Ahmedabad, Gujarat, India.
Introduction: Renal cell carcinoma (RCC) accounts for 2-3% of adult malignant tumors, often metastasizing to bones, especially the spine. Spinal metastasis has a poor prognosis, but solitary spinal tumors have better outcomes with targeted chemotherapy, radiotherapy, and newer surgical approaches. Due to RCC's high vascularity and resistance to treatments, en bloc vertebrectomy with anterior and posterior fixation is the gold standard for solitary lesions.
View Article and Find Full Text PDFSurg Case Rep
November 2024
Division of Thoracic Surgery, Shizuoka Cancer Center, Shimonagakubo 1007, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Background: Thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is a high-grade malignant neoplasm with a poor prognosis. Most cases of SMARCA4-UT have extensive chest wall and mediastinum involvement. The efficacy of surgical resection has not been clearly established.
View Article and Find Full Text PDFNeurosurg Rev
October 2024
Department of Neurosurgery, University of Colorado, Denver, CO, USA.
There is a paucity of data available on the context preceding anterior fusion failure or the need for a posterior fusion, the timing of the second operation, or any correlation between the different instrumentation and failure rates. A retrospective chart review was performed of 131 identified patients who underwent anterolateral corpectomy and fusion for a thoracolumbar burst fracture from 2000 to 2012 in a single institution. 96 patients had clinical and radiographic follow up of greater than two months.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
September 2024
From the Reconstructive Microsurgery Section, Division of Plastic, Reconstructive and Aesthetic Surgery, Dr. Cipto Mangunkusumo National Hospital, Universitas Indonesia, Jakarta, Indonesia.
In the context of tuberculous spondylitis, a rare form of extrapulmonary tuberculosis causing significant discomfort and neurological deficits, surgery becomes imperative to alleviate symptoms alongside antituberculosis treatment. However, the utilization of free vascularized fibula flaps for repairing vertebral deformities remains uncommon. This report presents the case of a 21-year-old man with limb weakness and sensory disturbances who was referred to our hospital, where contrast magnetic resonance imaging revealed a paravertebral abscess spanning several thoracic vertebrae.
View Article and Find Full Text PDFJ Clin Med
September 2024
Department of Orthopaedics and Trauma Surgery, Division of Orthopaedics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
: We evaluated the outcomes of patients undergoing en bloc total vertebrectomy at our institution within the last three decades. The aim of our study was to analyse the oncological and neurological outcomes and the changes over time. : We included 22 consecutive patients treated with a total vertebrectomy at our institution between January 1990 and December 2022.
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