Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Cardiovascular diseases are among the leading causes of death in the world. The coronary blockage is one of most common types of these diseases that in the majority of cases has been treated by bypass surgery. In the bypass surgery, a graft is implemented to alter the blocked coronary and allow the blood supply process. The hemodynamic characteristics of the bypass strongly depend on the geometry and mechanical properties of the graft. In the present study, the fluid-structure interaction (FSI) analysis is conducted to investigate the bypass performance for a thoracic artery as well as a saphenous vein graft. Blood flow introduces a pressure on the walls of the graft which behaves as a hyperelastic material. A complete coronary bypass with stenosis degrees of 70% and 100% is modeled. To consider the nonlinear stress-strain behavior of the grafts, a five parameter Mooney-Rivlin hyperplastic model is implemented for the structural analysis and blood is assumed to behave as a Newtonian fluid. The simulations are performed for a structured grid to solve the governing equations using finite element method (FEM). The results show that wall shear stress (WSS) for saphenous vein is larger than that of thoracic artery while the total deformation of the thoracic artery is larger compared to the saphenous vein. Also, for the venous grafts or lower stenosis degree, the oscillatory shear index (OSI) is higher at both left and right anastomoses meaning that venous grafts as well as lower degree of stenosis are more critical in terms of restenosis.
Download full-text PDF |
Source |
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http://dx.doi.org/10.1080/10255842.2020.1857744 | DOI Listing |
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