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Effectiveness of an Innovative Cognitive Treatment and Telerehabilitation on Subjects With Mild Cognitive Impairment: A Multicenter, Randomized, Active-Controlled Study. | LitMetric

AI Article Synopsis

  • The study evaluated the effectiveness of a virtual reality rehabilitation system (VRRS) for cognitive training in individuals with mild cognitive impairment (MCI) compared to traditional face-to-face cognitive treatments.
  • A total of 49 participants were randomly assigned to different treatment groups, including VRRS followed by telerehabilitation, VRRS followed by unstructured cognitive stimulation, and standard treatment.
  • Results showed that VRRS improved memory and language skills more than traditional methods, and telerehabilitation helped maintain these cognitive gains better than unstructured stimulation.

Article Abstract

Background: In recent years, the potential usefulness of cognitive training procedures in normal aging and mild cognitive impairment (MCI) have received increased attention.

Objective: The main aim of this study was to evaluate the efficacy of the face-to-face cognitive virtual reality rehabilitation system (VRRS) and to compare it to that of face-to-face cognitive treatment as usual for individuals with MCI. Moreover, we assessed the possibility of prolonging the effects of treatment with a telerehabilitation system.

Methods: A total of 49 subjects with MCI were assigned to 1 of 3 study groups in a randomized controlled trial design: (a) those who received face-to-face cognitive VRRS (12 sessions of individualized cognitive rehabilitation over 4 weeks) followed by telerehabilitation (36 sessions of home-based cognitive VRRS training, three sessions for week); (b) those who received face-to-face cognitive VRRS followed by at-home unstructured cognitive stimulation (36 sessions of home-based unstructured cognitive stimulation, three sessions for week); and (c) those who received face-to-face cognitive treatment as usual (12 sessions of face-to-face cognitive treatment as usual).

Results: An improvement in memory, language and visuo-constructional abilities was observed after the end of face-to-face VRRS treatment compared to face-to-face treatment as usual. The application of home-based cognitive VRRS telerehabilitation seems to induce more maintenance of the obtained gains than home-based unstructured stimulation.

Discussion: The present study provides preliminary evidence in support of individualized VRRS treatment and telerehabilitation delivery for cognitive rehabilitation and should pave the way for future studies aiming at identifying optimal cognitive treatment protocols in subjects with MCI.

Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT03486704.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701275PMC
http://dx.doi.org/10.3389/fnagi.2020.585988DOI Listing

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