Today's global health challenges in underserved communities include the growing burden of cancer and other non-communicable diseases (NCDs); infectious diseases (IDs) with epidemic and pandemic potential such as COVID-19; and health effects from catastrophic 'all hazards' disasters including natural, industrial or terrorist incidents. Healthcare disparities in low-income and middle-income countries and in some rural areas in developed countries make it a challenge to mitigate these health, socioeconomic and political consequences on our globalised society. As with IDs, cancer requires rapid intervention and its effective medical management and prevention encompasses the other major NCDs. Furthermore, the technology and clinical capability for cancer care enables management of NCDs and IDs. Global health initiatives that call for action to address IDs and cancer often focus on each problem separately, or consider cancer care only a downstream investment to primary care, missing opportunities to leverage investments that could support broader capacity-building. From our experience in health disparities, disaster preparedness, government policy and healthcare systems we have initiated an approach we call which emphasises a systems approach from the outset of program building that integrates investment among IDs, cancer, NCDs and disaster preparedness to improve overall healthcare for the local community. This approach builds on trusted partnerships, multi-level strategies and a healthcare infrastructure providing surge capacities to more rapidly respond to and manage a wide range of changing public health threats.
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http://dx.doi.org/10.1136/bmjgh-2020-003252 | DOI Listing |
Objective: this retrospective study aimed to evaluate the impact of BRCA mutational status on the outcomes of patients with advanced ovarian cancer treated with either primary debulking surgery (PDS) or neoadjuvant chemotherapy followed by interval debulking surgery (NACT-IDS). Material and a total of 79 patients with stage III-IV ovarian cancer treated at Elias Emergency University Hospital between January 2014 and March 2024 were included. Patients received either PDS followed by chemotherapy or NACT-IDS.
View Article and Find Full Text PDFAging Clin Exp Res
December 2024
Department of Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Background & Aims: Surgery combined with chemotherapy remains the mainstay of treatment for advanced epithelial ovarian cancer. It is important to evaluate the occurrence of postoperative complications before operation and to prevent them. The purpose of this study is to investigate the role of sarcopenia diagnosed by CT scans in predicting postoperative complications in patients with ovarian cancer.
View Article and Find Full Text PDFData Brief
December 2024
Department of Electrical and Computer Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada.
Quantum field lens coding algorithm (QF-LCA) dataset is useful for simulating systems and predict system events with high probability. This is achieved by computing QF lens distance-based variables associated to event probabilities from the dataset produced by field lenses that encode system states on a quantum level. The probability of a state transition (ST), doubles in prediction values at the decoding step, e.
View Article and Find Full Text PDFJ Cancer
October 2024
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11421, Saudi Arabia.
Cancer Med
December 2024
Department of Pediatric Hematology and Oncology, University Hospital Bonn, Bonn, Germany.
Purpose: The shift from child-centered to adult-focused healthcare presents social and psychological challenges for adolescents and young adults with chronic conditions, which can affect their participation in follow-up care. This study aims to investigate the factors that influence patient-driven motivations for adhering to follow-up recommendations, while also exploring the barriers and supports that impact the transition process for pediatric cancer survivors.
Methods: We developed interview guidelines grounded in the Theory of Planned Behavior (TPB) and the stereotype priming model (SPM).
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