Phagocytes engulf pathogens into a membrane bound compartment called a phagosome, but what happens when engulfed pathogens start growing? In this issue of Cell Host & Microbe,Westman et al. (2020) show that lysosomes fuse with phagosomes to maintain phagosomal membrane integrity as the fungal pathogen Candida albicans expands.
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http://dx.doi.org/10.1016/j.chom.2020.11.005 | DOI Listing |
Gels
October 2024
College of Petroleum Engineering and Geosciences, King Fahd University of Petroleum & Minerals, Dhahran 31261, Saudi Arabia.
Silicate gels have long been utilized as water shut-off agents in petroleum fields to address excessive water production. In recent years, nano-silica gel has emerged as a promising alternative to traditional silicate gels, offering potentially improved plugging performance. However, the long-term effectiveness of these gels remains uncertain, posing challenges to sustained profitability.
View Article and Find Full Text PDFAuris Nasus Larynx
October 2024
Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
We report a challenging and uncommon case involving a 53-year-old Japanese man with cerebrospinal fluid (CSF) leakage caused by a meningocele in the lateral recess of the sphenoid sinus. Our innovative treatment approach involved a combination of transpterygoid and endoscopic modified medial maxillectomy techniques, with special emphasis on the preservation of the sphenopalatine artery. This strategic preservation was pivotal to the successful use of the ipsilateral nasoseptal flap for reconstruction, which played a crucial role in the prevention of postoperative CSF leakage.
View Article and Find Full Text PDFSurg Neurol Int
July 2024
Assistant Clinical Professor of Orthopedics, NYU Langone Hospital, Long Island, NY, USA, 1122 Franklin Avenue Suite 106, Garden City, NY, USA.
Catheter Cardiovasc Interv
September 2024
Department of Cardiology, Cardiovascular Institute, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Asian J Neurosurg
June 2024
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Large pituitary adenoma often pushes the diaphragma sella and extends to the suprasellar compartment. The thinned out diaphragma may get opened during endonasal endoscopic surgery and pose high risk for cerebrospinal fluid (CSF) leak. Such larger defects are difficult to plug with fat graft that tends to slip in to the subarachnoid space.
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