Plugging a Leak: How Phagosomes "Stretch" to Accommodate Pathogen Growth.

Cell Host Microbe

Institute of Microbiology & Infection and School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. Electronic address:

Published: December 2020

Phagocytes engulf pathogens into a membrane bound compartment called a phagosome, but what happens when engulfed pathogens start growing? In this issue of Cell Host & Microbe,Westman et al. (2020) show that lysosomes fuse with phagosomes to maintain phagosomal membrane integrity as the fungal pathogen Candida albicans expands.

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http://dx.doi.org/10.1016/j.chom.2020.11.005DOI Listing

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