AI Article Synopsis
- Intestinal microbiota plays a crucial role in developing the immune system and food tolerance during early life.
- Disruptions in the colonization of gut bacteria can lead to chronic inflammatory and autoimmune diseases later in life.
- Factors like caesarean section delivery and antibiotic use can negatively impact gut microbiota, highlighting the need to minimize their use to support healthy colonization.
Article Abstract
Intestinal microbiota affects many aspects of physiological processes. The type of microbiota in the early stages of life is a critical element conditioning the development of the immune response and food tolerance. Disturbed colonization of the digestive tract resulting from the amount or diversity of bacteria colonies stimulates an inflammatory response that is associated in later life with inflammatory and autoimmune diseases. One of the elements disturbing normal colonization in the perinatal period is the operative way of delivery by caesarean section and the administration of antibiotics, used as a prophylactic measure as well as for therapeutic reasons. Based on the current state of knowledge, there is a lot of evidence demonstrating the long-term adverse effects of these modifying agents for gut microbiota, which should be kept to a minimum as far as possible.
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| http://dx.doi.org/10.5603/GP.2020.0114 | DOI Listing |
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