Selective transmembrane transport of Aβ protein regulated by tryptophan enantiomers.

Chem Commun (Camb)

Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.

Published: January 2021

Tryptophan enantiomers (d/l-Trp) were introduced into artificial nanochannels to regulate the chiral selective transport of Aβ proteins. The l-Trp channel performs effectively selectivity for the transport of Aβ protein, which would provide a new perspective for the pathological studies of Alzheimer's disease.

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Source
http://dx.doi.org/10.1039/d0cc06104bDOI Listing

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