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New Technique to Analyze the Breath Sound Spectrum in Children with Asthma. | LitMetric
Objective : Breath sound parameters have been reported as useful biomarkers for evaluating the airway condition.Methods : The reliability of breath sound analysis using an improved method was investigated. Eighty-three asthmatic children were included in the present study. After adjusting the 0 level based on the background noises of the breath sound spectrum, the total area under the curve of the dBm (A), the roll-off from 600-1200 Hz (Slope), the ratio of the third and fourth area to the A (A/A and B/A), and the ratio of power and frequency at 50% and 75% of the highest frequency (RPF and RPF), were evaluated before and after β agonist inhalation. Spirography and the forced oscillation technique were also used to evaluate all subjects.Results : Using the new method, A/A, B/A, RPF and RPF, were significantly increased after β agonist inhalation. The increase in A/A and B/A were significantly correlated with the increase in FEV and FEE, and the increase in RPF was reversibly correlated with that in R5-R20.Conclusions : The spectrum curve indices using the adjusted 0 level can indicate bronchial dilation with β agonist inhalation. These parameters may be useful for the assessment of bronchial reversibility in asthmatic children.
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