Stereotactic irradiation appears to be effective in causing partial or complete thrombosis of AVM that are not surgically resectable. Use of heavy particles generated in a cyclotron allows better spatial definition and dose distribution than do other methods, allowing larger AVM to be treated. From these preliminary results, it is evident that heavy-particle irradiation therapy, like proton beam therapy, does not offer protection from recurrent hemorrhage for at least 12 months, nor is it devoid of major complications; it does offer a noninvasive mode of therapy for AVM that are difficult to treat surgically, however.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Accuracy Evaluation of Dose Warping Using Deformable Image Registration in Carbon Ion Therapy.
Int J Part Ther
March 2025
Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
Purpose: The study's purpose was to use a simple geometry phantom to validate the deformable image registration (DIR) accuracy and dose warping accuracy in carbon ion radiotherapy (CIRT) and to provide an index for dosimetry in CIRT.
Materials And Methods: We used geometric and anatomical phantoms provided by AAPM TG-132. The DIRs of 3 different settings were performed between reference and translational images for each phantom.
Rectal Gas-Induced Dose Changes in Carbon Ion Radiation Therapy for Prostate Cancer: An In Silico Study.
Int J Part Ther
March 2025
Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
Purpose: This study aims to determine dosimetric influence of rectal gas in carbon ion radiation therapy (CIRT) for prostate cancer and to establish a procedure for removal rectal gas in clinical scenarios.
Materials And Methods: We analyzed 18 prostate cancer cases with bulky rectal gas. The dose distribution was recalculated on computed tomography (CT) with bulky rectal gas (gasCT) after creating the initial plan on a CT without bulky rectal gas, and the doses were transformed using a displacement vector field.
Intratumoral Transforming Boron Nanosensitizers for Amplified Boron Neutron Capture Therapy.
Angew Chem Int Ed Engl
January 2025
The Radiology Department of Shanxi Provincial People's Hospital Affiliated to, Shanxi Medical University, Taiyuan, 030001, P. R. China.
Boron neutron capture therapy (BNCT) is an advanced binary tumor-cell-selected heavy-particle radiotherapy used for treating invasive malignant tumors. However, its clinical applications have been impeded by the rapid metabolism and insufficient tumor-specific accumulation of boron agents. To tackle this issue, we develop a smart boron nanosensitizer (BATBN) capable of transforming its size in response to cancer biomarker for optimal balance between penetration and retention of boron-10 for BNCT.
View Article and Find Full Text PDFVerification of linear energy transfer optimized carbon-ion radiotherapy.
Phys Med Biol
November 2024
Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba, Japan.
Linear energy transfer (LET) verification was conducted using a silicon-on-insulator (SOI) microdosimeter during the commissioning of LET-optimized carbon-ion radiotherapy (CIRT). This advanced treatment technique is expected to improve local control rates, especially in hypoxic tumors.An SOI microdosimeter with a cylindrical sensitive volume of 30m diameter and 5m thickness was used.
View Article and Find Full Text PDFTreatment Planning Comparison of Gantry-based and Fixed Beams for the Treatment of Liver Tumors With Carbon Ion Therapy.
In Vivo
October 2024
Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
Background/aim: This study aimed to compare the use of a rotating gantry in liver tumor carbon-ion radiotherapy using of a fixed-port for treatment planning.
Materials And Methods: Thirty patients with liver tumors were analyzed. Three treatment plans were developed for each case: one with a rotating gantry with a 360° angle, one with fixed ports of 0° and 90° with a ±20° couch rolling setting, and one with fixed ports of 45° and 90° with a ±20° couch rolling setting.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!