Objective: The objective of this study is to investigate the allergen sensitization pattern among 4,203 children in the Shanxi region of China and to provide guidance for diagnosis and prevention of allergic diseases.
Methods: A retrospective analysis was conducted on the allergen-specific immunoglobulin E (sIgE) results of 4,203 children aged 0-12 years from January to December in 2019. SIgE antibodies to 19 allergens in the serum sample were detected by enzyme ALLERGO-SORBENT testing.
Results: In total, 49.70% (2,089/4,203) of children with allergic diseases were positive for sIgE, and the top 5 allergens were egg white 18.63% (783/4,203), artemisia 14.47% (608/4,203), milk 13.04% (548/4,203), ragweed 8.66% (364/4,203), and poplar/willow/elm 8.52% (358/4,203). Significant differences in the positive rate of food allergens and aeroallergens in different ages were found (p < 0.05). 50.98% (1,065/2,089) patients were sensitive to 2 or more allergens. The high sensitization rate in the >3-year group was significantly higher than the ≤3-year group (p < 0.05).
Conclusion: Egg white and artemisia are the most common allergens in children in northern China. This study provides allergic sensitization pattern of children and clinical epidemiological data in the region.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000511976 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Molecular epidemiology of Hepatitis E virus among humans in the Niger Republic, 2017-2023.
J Clin Virol
January 2025
Virology department, Institut Pasteur de Dakar, 36. Avenue Pasteur Dakar, Dakar 220, Senegal.
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis, responsible for large outbreaks in resource limited countries. The virus belongs to the genus Orthohepevirus which is subdivided into eight distinct genotypes (HEV-1 to HEV-8). Human disease transmission is mostly through the faecal-oral route.
View Article and Find Full Text PDFIdentification and characterization of the Cul t 1 as major allergen from biting midge Culicoides tainanus.
Mol Immunol
January 2025
Department of Cell Biology, School of Preclinical Medicine, Zunyi Medical University, Zunyi, Guizhou 563003, China. Electronic address:
Background: Midges are widely distributed globally. They can transmit numerous serious diseases as well as trigger an allergic reaction in the host. Their saliva contains a variety of proteins that act as sensitizers to stimulate the host's immune response, leading to IgE-mediated allergic symptoms.
View Article and Find Full Text PDFMicroRNA-142-3p chemo-sensitizing breast cancer to docetaxel: apoptosis and cell cycle arrest induction, and migration suppression.
Vet Res Forum
November 2024
Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Docetaxel (DTX) is widely utilized in breast cancer treatment. However, cancer cell resistance has limited its anti-tumor efficacy. Some molecules called microRNAs (miRNAs), acting like fine-tuned switches, can influence how breast cancer develops and spreads.
View Article and Find Full Text PDFUncovering Molecular Sensitization Patterns for Peanut in East-Central European Children: The Dominance of Ara h 6.
Mol Cell Probes
January 2025
Heim Pál National Institute of Pediatrics, Üllői u. 86, 1089 Budapest, Hungary; Semmelweis University, Dep. Family Care Methodology, Üllői út 26, 1085 Budapest, Hungary.
Tell me what to expect: how instructions affect the pain response of patients with chronic myofascial pain with referral.
J Oral Facial Pain Headache
December 2024
Neuroscience of Emotion Cognition and Nociception Group (NeuroCEN Group), Faculty of Odontology, Complutense University of Madrid, 28040 Madrid, Spain.
The aims of the study are to analyze the influence of pain and no pain expectations on the physiological (electromyography (EMG) and pupillometry) and cognitive (Numerical Rating Scale (NRS)) response to pain. Pain expectation and no pain expectation situations were induced by employing instructional videos. The induction of pain was performed by palpating the masseter with an algometer in a sample of 2 groups: 30 healthy participants (control group) and 30 patients (Temporomandibular disorders (TMD) group) with chronic myofascial pain with referral in the masseter muscle (Diagnostic Criteria for Temporomandibular Dissorders (DC/TMD)).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!