Hypertrophic cardiomyopathy (HCM) is the most common heart disease with a genetic origin, and its main characteristic is left ventricular hypertrophy that occurs in the absence of other conditions that trigger this change. HCM may present from asymptomatic forms to manifestations of sudden cardiac death and severe heart failure. Contemporary high-resolution imaging methods and more accurate clinical scores have been used and developed to provide a prognostic assessment and adequate functional assessments, as well as to allow for the stratification of clinical severity. These aspects will be addressed in this review, along with other classic topics inherent to the study of this disease.
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http://dx.doi.org/10.36660/abc.20190802 | DOI Listing |
JACC Adv
February 2025
Division of Cardiology, Atlantic Health, New Jersey, USA.
Background: The Valsalva maneuver is essential in evaluating left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic cardiomyopathy (HCM). Traditionally, a self-directed Valsalva (SDV) maneuver is taught to patients using vague instructions such as "bear down." SDV is often not performed correctly leading to variable results and underestimation of the true provocable LVOT gradient.
View Article and Find Full Text PDFJACC Adv
February 2025
Barts Heart Centre, Department of Cardiac Diagnostics and The Inherited Cardiovascular Diseases Unit, St Bartholomew's Hospital, London, United Kingdom.
JACC Adv
February 2025
Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
J Am Soc Echocardiogr
January 2025
Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke's Medical Centers, Aurora Health Care, Milwaukee, WI. Electronic address:
Phys Eng Sci Med
January 2025
School of Electrical Engineering and Electronic Information, Xihua University, Chengdu, China.
Hypertrophic cardiomyopathy (HCM), including obstructive HCM and non-obstructive HCM, can lead to sudden cardiac arrest in adolescents and athletes. Early diagnosis and treatment through auscultation of different types of HCM can prevent the occurrence of malignant events. However, it is challenging to distinguish the pathological information of HCM related to differential left ventricular outflow tract pressure gradients.
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