Objective: to estimate prevalence and factors associated with the consumption of psychoactive substances among health care workers in hospitals.
Method: cross-sectional study, with a sample of 289 health care professionals in a large hospital in Teresina, Piauí, Brazil.
Results: 243 (84.1%) reported consumption of psychoactive substances; 124 (86.7%) of professionals who classed their level of satisfaction as moderate had double the chance (OR = 1.98 CI95% 1.02- 3.85) of consuming psychoactive substances; 40 (93%) of those with low level of satisfaction showed a four times higher chance (OR = 4.05 CI95% 1.15-14.26) of consumption; and 72 (75.8%) of those who reported a "good" state of health before work had a 54% lower chance of consumption (OR= 0.46 CI95% 0.234-0919).
Conclusion: consumption of psychoactive substances was associated with factors related to level of job satisfaction and perceived health status before work.
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http://dx.doi.org/10.1590/0034-7167-2020-0279 | DOI Listing |
J Clin Med
January 2025
Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, College Lane Campus, Hatfield, Hertfordshire AL10 9AB, UK.
Alkyl nitrites are a class of inhalant, commonly known as 'poppers'. Although having medical uses, some other effects include a 'rush', 'high', 'euphoria', or feeling of excitement. This has led to their recreational use, in different scenarios, since the mid-1960s.
View Article and Find Full Text PDFMolecules
January 2025
Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
New psychoactive substances (NPSs) emerged in the 2000s as legal alternatives to illicit drugs and quickly became a huge public health threat due to their easy accessibility online, limited information, and misleading labels. Synthetic cannabinoids and synthetic cathinones are the most reported groups of NPSs. Despite NPSs being widely studied, due to their structural diversity and the constant emergence of novel compounds with unknown properties, the development of new techniques is required to clarify their mode of action and evaluate their toxicological effects.
View Article and Find Full Text PDFToxicol Res (Camb)
February 2025
Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Synthetic cathinones (SCs), a group of new psychoactive substances (NPS), are designer molecules with hallucinogenic and psychostimulatory effects. Although the structural similarities of SCs to amphetamines suggest that they may have similar toxicity profiles to those of amphetamine congeners, little is known about SCs from a toxicological point of view. In the present study, the toxicity profiles of commonly encountered SCs ( = 65), listed in the 2020 Report of the United Nations Office on Drugs and Crime (UNODC), were evaluated using in silico methods.
View Article and Find Full Text PDFRev Med Suisse
January 2025
Unité des dépendances, Service de médecine de premier recours, Hôpitaux universitaires de Genève, 1211 Genève 14.
The use of psychoactive substances affects more men than women, with a prevalence that is 1.3 to 2 times higher, except for the use of sedatives. Men are also more affected by accidents, injuries, and acts of violence.
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