Outbreak of SARS-CoV-2 infection at a large refugee shelter in Toronto, April 2020: a clinical and epidemiologic descriptive analysis.

CMAJ Open

Crossroads Clinic (Redditt, Wright, Rashid, Male), Women's College Hospital; Department of Family & Community Medicine (Redditt, Rashid), and Lawrence S. Bloomberg Faculty of Nursing (Wright), University of Toronto; Divisions of General Internal Medicine and Infectious Diseases (Bogoch), University Health Network; Faculty of Medicine (Bogoch), University of Toronto, Toronto, Ont.

Published: December 2020

Background: There is high risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in congregate settings, including shelters. This study describes a coronavirus disease 2019 (COVID-19) outbreak and corresponding reported symptomatology at a shelter in Toronto.

Methods: This clinical and epidemiologic analysis focuses on a COVID-19 outbreak at a dedicated refugee shelter in downtown Toronto. All adult residents on site at the shelter were offered SARS-CoV-2 testing on Apr. 20, 2020. At the time of testing, residents were screened for 3 typical COVID-19 symptoms (fever, cough and shortness of breath). Among those who tested positive, a more comprehensive clinical assessment was conducted 1 day after testing and a standardized 15-item symptom screen was administered by telephone 14 days after testing. We report rates of positive test results and clinical symptoms with each assessment interval.

Results: Of the 63 adult residents on site at the shelter, 60 agreed to be tested. Among those tested, 41.7% ( = 25) were positive for SARS-CoV-2 infection. Of those who tested positive ( = 25), 20.0% ( = 5) reported fever, cough or shortness of breath at the time of testing. On more detailed assessment 1 day later, 70.8% (17/24) reported a broader range of symptoms. During the 14 days after testing, 87.5% (21/24) reported symptoms of infection.

Interpretation: We found a high rate of SARS-CoV-2 infection in this shelter population. Our study underscores the high risk of SARS-CoV-2 transmission in congregate living settings and the importance of mobilizing timely testing and management of symptomatic, paucisymptomatic and asymptomatic residents in shelters.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743908PMC
http://dx.doi.org/10.9778/cmajo.20200165DOI Listing

Publication Analysis

Top Keywords

sars-cov-2 infection
12
refugee shelter
8
clinical epidemiologic
8
high risk
8
covid-19 outbreak
8
adult residents
8
residents site
8
site shelter
8
time testing
8
fever cough
8

Similar Publications

CD8+ T cells are critical for immune protection against severe COVID-19 during acute infection with SARS-CoV-2. However, the induction of antiviral CD8+ T cell responses varies substantially among infected people, and a better understanding of the mechanisms that underlie such immune heterogeneity is required for pandemic preparedness and risk stratification. In this study, we analyzed SARS-CoV-2-specific CD4+ and CD8+ T cell responses in relation to age, clinical status, and inflammation among patients infected primarily during the initial wave of the pandemic in France or Japan.

View Article and Find Full Text PDF

Background: Health misinformation undermines responses to health crises, with social media amplifying the issue. Although organizations work to correct misinformation, challenges persist due to reasons such as the difficulty of effectively sharing corrections and information being overwhelming. At the same time, social media offers valuable interactive data, enabling researchers to analyze user engagement with health misinformation corrections and refine content design strategies.

View Article and Find Full Text PDF

Regulation and Compliance in Telemedicine: Viewpoint.

J Med Internet Res

January 2025

Doxy.me Research, Doxy.me, Inc, Charleston, SC, United States.

The US COVID-19 Public Health Emergency ended on May 11, 2023. Lawmakers and regulators extended some flexibilities while they deliberate effective long-term telemedicine policy. Here, we discuss critical challenges in telemedicine compliance and regulation grounded in scholarly literature and current events.

View Article and Find Full Text PDF

Background: This study was aimed to explore the global burden and trends of Clostridioides difficile infections (CDI) associated diseases.

Methods: Data for this study were obtained from the Global Burden of Disease Study 2021. The burden of CDI was assessed using the age-standardized rates of disability-adjusted life years (ASR-DALYs) and deaths (ASDRs).

View Article and Find Full Text PDF

The recent COVID-19 pandemic offers a rare opportunity to understand how citizens attribute responsibility for governments' responses to unanticipated negative-and in this case, systemic-exogenous shocks. Classical accounts of responsibility are complicated when crises are pervasive, involve multiple valence dimensions, and where individuals can make relative assessments of performance. We fielded a conjoint experiment in 16 countries with 22,147 respondents.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!