Emergence of ancient convalescent plasma (CP) therapy: To manage COVID-19 pandemic.

Transfus Clin Biol

Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa. Electronic address:

Published: February 2021

AI Article Synopsis

  • The COVID-19 pandemic, caused by the novel SARS-CoV-2 virus, has posed serious health risks globally since December 2019, with limited treatment options available.
  • Convalescent plasma (CP) therapy, an ancient immunotherapeutic method, is proposed as a potentially effective and immediate response to manage the infection.
  • While CP therapy has shown positive effects against COVID-19, its long-term use has not been recommended, highlighting the need for further exploration of its application.

Article Abstract

Since December 2019, the human populations of the 195 global countries continue experiencing grave health and life threats due to the current COVID-19 pandemic. As a result of the novelty of the pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at present there is lack of preventive as well as therapeutic options for treating and managing the infection. The use of ancient immunotherapeutic technique - the convalescent plasma (CP) therapy, may act as an immediate and available option to control the COVID-19 pandemic. This review provides a concept and understanding on the CP therapy, its potential to control SARS-CoV-2 pandemic. The CP therapy might act as an immediate saviour for society from the virus. Although the CP therapy has exert affirmative result against COVID-19 it has not been recommended for long time use in COVID-19 and this review gives support for its possible application.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718590PMC
http://dx.doi.org/10.1016/j.tracli.2020.11.004DOI Listing

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