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D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction. | LitMetric

AI Article Synopsis

Article Abstract

Coronavirus disease 2019 (COVID-19) mainly manifests as a respiratory syndrome, besides causing other complications. Severe COVID-19 may also present with coagulopathy, leading to venous thrombosis and cerebral infarction. Generally, acute stroke is a secondary complication in patients displaying respiratory syndromes. Here, we present a case of acute stroke in an 84-year-old female patient who did not manifest any respiratory symptoms. The patient had no cough or fever before the stroke onset; nevertheless, COVID-19 PCR test was positive. The patient also had markedly elevated serum D-dimer levels. Our findings suggest that coagulopathy can occur even in a patient with asymptomatic COVID-19 infection, and to our knowledge, this is the first report of such a case. We concluded that elevated D-dimer levels can serve as an additional COVID-19 screening tool in stroke patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703229PMC
http://dx.doi.org/10.1016/j.ensci.2020.100294DOI Listing

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