Antibacterial Efficacy of Calcium Hydroxide with Iodoform versus Calcium Hydroxide with Camphorated Paramonochlorophenol as Intrachannel Pastes on an Biofilm: A Comparative Study.

Objective: The objective of this study was to assess the antibacterial efficacy of Ca(OH) with iodoform versus Ca(OH) with camphorated paramonochlorophenol as intrachannel pastes on an biofilm.

Materials And Methods: The diffusion method was used in wells. The strain used was ATCC 29212. Bile esculin agar was inoculated into 60-well plates of 5 mm in diameter. Three groups were formed: Group 1: Calen PMCC (Ca(OH) + camphor paramonochlorophenol); Group 2: Metapex (Ca(OH) + iodoform); and Group 3: camphor paramonochlorophenol inoculated with as a positive control. The plates were then incubated at 37°C for 24 h. Bacterial inhibition halos were read.

Results: Group 1 presented the highest antimicrobial efficacy with a mean of 16.2 ± 0.6 mm, whereas Group 2 only had an antimicrobial effect of 9.7 ± 1.3 mm. Finally, Group 3 only exposed to the positive control (camphor paramonochlorophenol) showed an effect of 14.6 ± 1.0 mm. The inferential analysis showed statistically significant differences between the antimicrobial effect of the three groups ( = 0.001).

Conclusion: Ca(OH) paste with camphor paramonochlorophenol (Calen PMCC) has a greater antibacterial action on . The iodoform-associated Ca(OH) paste (Metapex) showed significantly lower antibacterial action against ( < 0.05).