AI Article Synopsis
- Dopamine is a crucial neurotransmitter involved in various biological processes, and its dysfunction can contribute to developmental disorders like ADHD, autism, and schizophrenia.
- The exact mechanisms of how dopaminergic signaling affects these disorders remain unclear, which is why this analysis focuses on its role in brain development and related conditions.
- The review aims to enhance understanding of dopaminergic signaling in developmental disorders, potentially guiding future research and the development of better therapeutic treatments.
Article Abstract
Dopamine (DA), a critical neurotransmitter of both the central and peripheral nerve system, plays important roles in a series of biological processes. Dysfunction of dopaminergic signalling may lead to a series of developmental disorders, including attention deficit/hyperactivity disorder, autism and schizophrenia. However, the exact roles of dopaminergic signalling in these diseases are far from fully understood. We analyse the roles of dopaminergic signalling in multiple physiological and pathological processes, focusing on brain development and related disorders. By summarizing current research in this area, we provide guidance for future studies. This review seeks to deepen our understanding of dopaminergic signalling in developmental disorders, which may offer clues for developing more effective therapeutic drugs.
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| http://dx.doi.org/10.1016/j.neulet.2020.135540 | DOI Listing |
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