Vaccination during the First Diagnosis of Multiple Myeloma: A Cohort Study of the French National Health Insurance Database.

Vaccines (Basel)

Service de Pharmacologie Médicale et Clinique, CHU de Toulouse, 31000 Toulouse, France.

Published: December 2020

Purpose: Infections are frequent and often result in serious complications in patients with multiple myeloma (MM). Prophylactic vaccination is recommended for influenza virus, , and . The aims of this study were to measure the vaccination rates within 24 months after the diagnosis of multiple myeloma and to identify factors associated with vaccine use.

Methods: MM patients were selected through the French national health insurance database from 1 January 2010 to 31 December 2015. Patients with a previous history of MM were excluded.

Results: Vaccination rates against influenza, and among 22,831 newly diagnosed MM patients were, respectively, 28.5%, 10.3%, and 1.4%. Only 0.7% received all three vaccines. Factors associated with vaccination were young age, male gender, an absence of comorbidity, a history of higher medication and vaccine consumption, Herpes simplex virus (HSV), Varicella zoster virus (VZV), and the use of pneumocystis prophylaxis.

Conclusion: The low rates of vaccination indicate the need to improve physician and MM patient adherence and education regarding vaccination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712872PMC
http://dx.doi.org/10.3390/vaccines8040722DOI Listing

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