Autophagy Brings an END to Aberrant Endocytosis.

Mol Cell

Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. Electronic address:

Published: December 2020

Wilfling et al. (2020) characterize a selective autophagy pathway in yeast for early clathrin-mediated endocytosis (CME) proteins facilitated by the phase separation of the CME protein, Ede1, which acts as an intrinsic autophagy receptor for the degradation of Ede1-dependent endocytic protein deposits (ENDs).

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Source
http://dx.doi.org/10.1016/j.molcel.2020.11.020DOI Listing

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